Thiosemicarbazone-benzenesulfonamide Derivatives as Human Carbonic Anhydrases Inhibitors: Synthesis, Characterization, and In silico Studies

Keyphrases

• In Silico Study 100%
• Carbonic Anhydrase Inhibitors 100%
• Ca(II) 100%
• Thiosemicarbazone 100%
• Isoenzymes 100%
• Carbonic Anhydrase 100%
• Benzenesulfonamide Derivatives 100%
• CA XII 100%
• CA I 100%
• Inhibitor Synthesis 100%
• Molecular Docking Studies 50%
• HCO3 50%
• Selective Inhibitor 50%
• Interconversion 50%
• Inhibitory Activity 50%
• Binding Mechanism 50%
• HCA II 50%
• Molecular Interactions 50%
• Novel Therapeutics 50%
• Human Carbonic Anhydrase 50%
• Metalloenzymes 50%
• HCA IX 50%
• Nanomolar Concentrations 50%
• Molecular Selectivity 50%
• Multiple Diseases 50%
• Tail Approach 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Carbonate Dehydratase Inhibitor 100%
• Thiosemicarbazone 100%
• Isoenzyme 100%
• Benzenesulfonamide Derivative 100%
• Carbonate Dehydratase 50%
• Carbonate Dehydratase I 50%
• Carbon Dioxide 50%
• Comorbidity 50%