The use of novel photobleachable phthalocyanines to image DNA

Burcu Turanli-Yildiz, Tuba Sezgin, Z. Petek Akar, Canan Uslan, B. Şebnem Sesalan*, Ahmet Gül

*Bu çalışma için yazışmadan sorumlu yazar

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19 Atıf (Scopus)

Özet

The interaction of cationic photobleachable cobalt 1 and palladium 2 phthalocyanines (pcs) with calf thymus (CT) DNA was investigated by UV/vis spectrophotometric methods and gel electrophoresis. With the addition of pcs, the change in the thermal denaturation profile of DNA was observed. The results indicated that these molecules exhibit efficient DNA binding activity. The new cationic cobalt derivative 1 was characterized by elemental analysis, UV, IR and mass spectrophotometry.

Orijinal dilİngilizce
Sayfa (başlangıç-bitiş)1720-1724
Sayfa sayısı5
DergiSynthetic Metals
Hacim161
Basın numarası15-16
DOI'lar
Yayın durumuYayınlandı - Ağu 2011

Finansman

This work was supported by the Research Funds of Istanbul Technical University (33851) and TUBITAK (110T527). We thank Dr. Barbaros Akkurt for UV/vis spectrophotometric measurements.

FinansörlerFinansör numarası
TUBITAK110T527
Istanbul Teknik Üniversitesi33851

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