Temperature-dependent optical properties of individual vascular wall components measured by optical coherence tomography

Freek J. Van Der Meer; Dirk J. Faber; Inci Çilesiz; Martin J.C. Van Gemert; Ton G. Van Leeuwen

doi:10.1117/1.2333613

Temperature-dependent optical properties of individual vascular wall components measured by optical coherence tomography

Freek J. Van Der Meer
, Dirk J. Faber
, Inci Çilesiz
, Martin J.C. Van Gemert
, Ton G. Van Leeuwen^*

^*Bu çalışma için yazışmadan sorumlu yazar

Elektronik ve Hab.Müh.Bölümü

University of Amsterdam
Royal Netherlands Academy of Arts and Sciences
University of Twente

Araştırma sonucu: Dergiye katkı › Makale › bilirkişi

40 Atıf (Scopus)

Özet

Optical properties of tissues and tissue components are important parameters in biomedical optics. We report measurements of tissue refractive index n and the attenuation coefficient μ_t using optical coherence tomography (OCT) of individual vascular wall layers and plaque components. Moreover, since the temperature dependence of optical properties is widely known, we compare measurements at room and body temperatures. A decrease of n and μ_t is observed in all samples, with the most profound effect on samples with high lipid content. The sample temperature is of influence on the quantitative measurements within OCT images. For extrapolation of ex-vivo experimental results, especially for structures with high lipid content, this effect should be taken into account.

Orijinal dil	İngilizce
Makale numarası	041120
Dergi	Journal of Biomedical Optics
Hacim	11
Basın numarası	4
DOI'lar	https://doi.org/10.1117/1.2333613
Yayın durumu	Yayınlandı - Tem 2006

Finansman

The authors wish to thank G. Pasterkamp and the Utrecht Athero-Express biobank for the donation of atherosclerotic samples. This research is sponsored by the Netherlands Heart Foundation (grant 99.199) and is also part of the research program of the “Stichting voor Fundamenteel Onderzoek der Materie (FOM),” which is financially supported by the Ned-erlandse Organisatie voor Wetenschappelijk Onderzoek (NWO). We acknowledge the Interuniversity Cardiology Institute of the Netherlands (ICIN) for financial support.

Finansörler	Finansör numarası
Netherlands Heart Foundation	99.199
Stichting voor Fundamenteel Onderzoek der Materie
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Foundation for Fundamental Research on Matter

Belgeye Erişim

10.1117/1.2333613

Diğer Dosyalar ve Linkler

Link to publication in Scopus

Alıntı Yap

@article{c50e8fd9b0c54067aeb9e19e596ec930,

title = "Temperature-dependent optical properties of individual vascular wall components measured by optical coherence tomography",

abstract = "Optical properties of tissues and tissue components are important parameters in biomedical optics. We report measurements of tissue refractive index n and the attenuation coefficient μt using optical coherence tomography (OCT) of individual vascular wall layers and plaque components. Moreover, since the temperature dependence of optical properties is widely known, we compare measurements at room and body temperatures. A decrease of n and μt is observed in all samples, with the most profound effect on samples with high lipid content. The sample temperature is of influence on the quantitative measurements within OCT images. For extrapolation of ex-vivo experimental results, especially for structures with high lipid content, this effect should be taken into account.",

keywords = "Optical coherence tomography, Temperature dependence, Vascular wall",

author = "\{Van Der Meer\}, \{Freek J.\} and Faber, \{Dirk J.\} and Inci {\c C}ilesiz and \{Van Gemert\}, \{Martin J.C.\} and \{Van Leeuwen\}, \{Ton G.\}",

year = "2006",

month = jul,

doi = "10.1117/1.2333613",

language = "English",

volume = "11",

journal = "Journal of Biomedical Optics",

issn = "1083-3668",

publisher = "SPIE",

number = "4",

}

TY - JOUR

T1 - Temperature-dependent optical properties of individual vascular wall components measured by optical coherence tomography

AU - Van Der Meer, Freek J.

AU - Faber, Dirk J.

AU - Çilesiz, Inci

AU - Van Gemert, Martin J.C.

AU - Van Leeuwen, Ton G.

PY - 2006/7

Y1 - 2006/7

N2 - Optical properties of tissues and tissue components are important parameters in biomedical optics. We report measurements of tissue refractive index n and the attenuation coefficient μt using optical coherence tomography (OCT) of individual vascular wall layers and plaque components. Moreover, since the temperature dependence of optical properties is widely known, we compare measurements at room and body temperatures. A decrease of n and μt is observed in all samples, with the most profound effect on samples with high lipid content. The sample temperature is of influence on the quantitative measurements within OCT images. For extrapolation of ex-vivo experimental results, especially for structures with high lipid content, this effect should be taken into account.

AB - Optical properties of tissues and tissue components are important parameters in biomedical optics. We report measurements of tissue refractive index n and the attenuation coefficient μt using optical coherence tomography (OCT) of individual vascular wall layers and plaque components. Moreover, since the temperature dependence of optical properties is widely known, we compare measurements at room and body temperatures. A decrease of n and μt is observed in all samples, with the most profound effect on samples with high lipid content. The sample temperature is of influence on the quantitative measurements within OCT images. For extrapolation of ex-vivo experimental results, especially for structures with high lipid content, this effect should be taken into account.

KW - Optical coherence tomography

KW - Temperature dependence

KW - Vascular wall

UR - https://www.scopus.com/pages/publications/33751330979

U2 - 10.1117/1.2333613

DO - 10.1117/1.2333613

M3 - Article

C2 - 16965148

AN - SCOPUS:33751330979

SN - 1083-3668

VL - 11

JO - Journal of Biomedical Optics

JF - Journal of Biomedical Optics

IS - 4

M1 - 041120

ER -

Temperature-dependent optical properties of individual vascular wall components measured by optical coherence tomography

Özet

Finansman

Belgeye Erişim

Diğer Dosyalar ve Linkler

Parmak izi

Alıntı Yap