@inproceedings{b091c1cc0b8e4f6aa49648be1dc8d9c7,
title = "Superresolution in scanning fluorescence microscopy by means of image processing in the optical domain",
abstract = "We present a new technique in scanning fluorescence microscopy with high-NA lenses that offers improved resolution over confocal imaging modes by employing new optical masks. The pattern of this 2D element, which both reflects and transmits the light in the final image plane into subsequent detectors, is calculated by a singular value decomposition of the imaging operator. It brings about instant optical processing to extend the effective bandwidth of the transfer function clearly beyond that of the confocal microscope and leads to a resolution enhancement of up to 50\%. We describe the development of the mask along with theoretical results.",
author = "U. Brand and J. Grochmalicki and G. Hester and I. Akduman and Pike, \{Edward R.M.D.\}",
year = "1996",
doi = "10.1117/12.260799",
language = "English",
isbn = "0819423289",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
pages = "216--227",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",
note = "Optical Biopsies and Microscopic Techniques ; Conference date: 07-09-1996 Through 07-09-1996",
}