Separation of positional isomers of aromatic anions by capillary electrophoresis using quaternized porphyrazine ion in aqueous solution

Separation of the positional isomers of chlorobenzoates and naphthalenesulfonates by capillary electrophoresis was investigated. A quaternized porphyrazine ion was synthesized and used as an additive in aqueous electrolytic solution. The positively charged macromolecule dynamically coated the surface of the fused silica capillary and reversed the direction of electroosmotic flow. The positional isomers of aromatic anions were well separated by the ion association reaction and possibly by π-π interaction between macrocyclic cation and aromatic anions.