Macroporous Surgical Mesh from a Natural Cocoon Composite

Yong Ming Chen; Lian Sheng Zang; Behlul Koc-Bilican; Ismail Bilican; Chris Holland; Demet Cansaran-Duman; Tugce Karaduman; Arzu Çolak; Yasin Bayır; Zekai Halici; Sevilay Ozmen; Asad Ali; Jalel Labidi; Caglar Elbuken; Murat Kaya

doi:10.1021/acssuschemeng.1c06941

Macroporous Surgical Mesh from a Natural Cocoon Composite

Yong Ming Chen, Lian Sheng Zang^*, Behlul Koc-Bilican, Ismail Bilican, Chris Holland, Demet Cansaran-Duman, Tugce Karaduman, Arzu Çolak, Yasin Bayır, Zekai Halici, Sevilay Ozmen, Asad Ali, Jalel Labidi, Caglar Elbuken, Murat Kaya^*

^*Bu çalışma için yazışmadan sorumlu yazar

Mol.Biyoloji ve Genetik Bölümü

Araştırma sonucu: ???type-name??? › Makale › bilirkişi

1 Atıf (Scopus)

Özet

Recently, traditional polymer-based surgical meshes have drawn unwanted attention as a result of host tissue complications arising from infection, biocompatibility, and mechanical compatibility. Seeking an alternative solution, we present a hierarchically structured nanofibrous surgical mesh derived from the naturally woven cocoon of the Japanese giant silkworm, termed MothMesh. We report that it displays nontoxicity, biocompatibility, suitable mechanical properties, and porosity while showing no adverse effect in animal trials and even appears to enhance cell proliferation. Hence, we assert that the use of this natural material may provide an effective and improved alternative to existing synthetic meshes.

Orijinal dil	İngilizce
Sayfa (başlangıç-bitiş)	5728-5738
Sayfa sayısı	11
Dergi	ACS Sustainable Chemistry and Engineering
Hacim	10
Basın numarası	18
DOI'lar	https://doi.org/10.1021/acssuschemeng.1c06941
Yayın durumu	Yayınlandı - 9 May 2022

Bibliyografik not

Publisher Copyright:
© 2022 American Chemical Society. All rights reserved.

Finansman

This study was funded by the Program of Introducing Talents to Chinese Universities (111 Program, D20023). The authors thanks the ASUBTAM (Aksaray University) for providing laboratory facilities and access to equipment.

Finansörler	Finansör numarası
Program of Introducing Talents to Chinese Universities
Higher Education Discipline Innovation Project	D20023

Belgeye Erişim

10.1021/acssuschemeng.1c06941

Diğer Dosyalar ve Linkler

Link to publication in Scopus

Alıntı Yap

Chen, Y. M., Zang, L. S., Koc-Bilican, B., Bilican, I., Holland, C., Cansaran-Duman, D., Karaduman, T., Çolak, A., Bayır, Y., Halici, Z., Ozmen, S., Ali, A., Labidi, J., Elbuken, C., & Kaya, M. (2022). Macroporous Surgical Mesh from a Natural Cocoon Composite. ACS Sustainable Chemistry and Engineering, 10(18), 5728-5738. https://doi.org/10.1021/acssuschemeng.1c06941

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title = "Macroporous Surgical Mesh from a Natural Cocoon Composite",

abstract = "Recently, traditional polymer-based surgical meshes have drawn unwanted attention as a result of host tissue complications arising from infection, biocompatibility, and mechanical compatibility. Seeking an alternative solution, we present a hierarchically structured nanofibrous surgical mesh derived from the naturally woven cocoon of the Japanese giant silkworm, termed MothMesh. We report that it displays nontoxicity, biocompatibility, suitable mechanical properties, and porosity while showing no adverse effect in animal trials and even appears to enhance cell proliferation. Hence, we assert that the use of this natural material may provide an effective and improved alternative to existing synthetic meshes.",

keywords = "biocompatibility, fibroin, sericin, surgical mesh, sustainable material, tissue engineering",

author = "Chen, {Yong Ming} and Zang, {Lian Sheng} and Behlul Koc-Bilican and Ismail Bilican and Chris Holland and Demet Cansaran-Duman and Tugce Karaduman and Arzu {\c C}olak and Yasin Bayır and Zekai Halici and Sevilay Ozmen and Asad Ali and Jalel Labidi and Caglar Elbuken and Murat Kaya",

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AU - Chen, Yong Ming

AU - Zang, Lian Sheng

AU - Koc-Bilican, Behlul

AU - Bilican, Ismail

AU - Holland, Chris

AU - Cansaran-Duman, Demet

AU - Karaduman, Tugce

AU - Çolak, Arzu

AU - Bayır, Yasin

AU - Halici, Zekai

AU - Ozmen, Sevilay

AU - Ali, Asad

AU - Labidi, Jalel

AU - Elbuken, Caglar

AU - Kaya, Murat

PY - 2022/5/9

Y1 - 2022/5/9

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AB - Recently, traditional polymer-based surgical meshes have drawn unwanted attention as a result of host tissue complications arising from infection, biocompatibility, and mechanical compatibility. Seeking an alternative solution, we present a hierarchically structured nanofibrous surgical mesh derived from the naturally woven cocoon of the Japanese giant silkworm, termed MothMesh. We report that it displays nontoxicity, biocompatibility, suitable mechanical properties, and porosity while showing no adverse effect in animal trials and even appears to enhance cell proliferation. Hence, we assert that the use of this natural material may provide an effective and improved alternative to existing synthetic meshes.

KW - biocompatibility

KW - fibroin

KW - sericin

KW - surgical mesh

KW - sustainable material

KW - tissue engineering

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SN - 2168-0485

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SP - 5728

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JO - ACS Sustainable Chemistry and Engineering

JF - ACS Sustainable Chemistry and Engineering

IS - 18

ER -

Macroporous Surgical Mesh from a Natural Cocoon Composite

Özet

Bibliyografik not

Finansman

Belgeye Erişim

Diğer Dosyalar ve Linkler

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Alıntı Yap