Identification of a 3-(5-methyl-2-thiazolylamino)phthalide as a new minor groove agent

Keyphrases

• Minor Groove 100%
• Single-stranded DNA (ssDNA) 100%
• Methyl 100%
• Phthalides 100%
• Escherichia Coli 66%
• Staphylococcus Aureus 66%
• Staphylococcus Epidermidis (S. epidermidis) 66%
• Molecular Dynamics Simulation 66%
• Anti-quorum Sensing Activity 66%
• MIC Values 66%
• Antibacterial Activity 66%
• UV-VIS Spectroscopy 33%
• Fourier Transform Infrared Spectroscopy (FT-IR) 33%
• Density Functional Theory 33%
• B3LYP 33%
• Pseudomonas Aeruginosa (P. aeruginosa) 33%
• Vibrational Frequencies 33%
• Amino 33%
• Binding Affinity 33%
• Monoclinic 33%
• Isobenzofuran-1(3H)-one 33%
• Unit Cell Parameters 33%
• P-base 33%
• Hybrid Functional 33%
• Geometry Optimization 33%
• Quantum Chemical Calculations 33%
• Irm-NMR 33%
• P. Mirabilis 33%
• Molecular Docking Calculations 33%
• Groove Binding 33%
• Single Crystal X-ray Analysis 33%
• Proteus Mirabilis 33%
• Chromobacterium Violaceum 33%
• Single-crystal X-ray Study 33%
• Docking Molecular 33%

Biochemistry, Genetics and Molecular Biology

• Dynamics 100%
• Single Crystal 100%
• Escherichia coli 100%
• Antibacterial Activity 100%
• Staphylococcus Aureus 100%
• Minimum Inhibitory Concentration 100%
• Staphylococcus Epidermidis 100%
• Quorum Sensing 100%
• X Ray 50%
• Proteus mirabilis 50%
• Chromobacterium violaceum 50%
• Binding Affinity 50%
• Pseudomonas aeruginosa 50%
• Docking (Molecular) 50%
• X-Ray Spectroscopy 50%
• Mirabilis 50%

Chemistry

• Antibacterial 100%
• MIC 100%
• UV/VIS Spectroscopy 50%
• DFT-B3LYP Calculation 50%
• Kd 50%
• Density Functional Theory 50%
• Vibrational Frequency 50%
• Monoclinic Space Group 50%
• Unit Cell Parameter 50%
• Quantum Chemical Calculations 50%
• NMR Spectroscopy 50%
• Single Crystal X-Ray Diffraction 50%
• Single Crystalline Solid 50%