Hemodynamic characterization of localized aortic valve calcifications

Reza Daryani, Emre Cenk Ersan, M. Serdar Çelebi

Araştırma sonucu: ???type-name???Konferans katkısıbilirkişi

1 Atıf (Scopus)

Özet

Different hemodynamic characteristics of the blood flow can be studied by numerical simulations of the blood flow around the heart valves, which are significantly useful in various fields such as recognition and prediction of cardiovascular diseases, valve surgery, replacement, and advanced design of patient-specific prosthetic valves. One of these common valvular diseases is aortic valve stenosis, which mainly occurs due to the decreased orifice area between the valves’ leaflets and leads to insufficient blood pumping. In the aortic valve, calcification is the main reason for stenosis in which calcium deposits on the leaflets increase their rigidity and consequently prevent them from fully opening and closing. Severe cases of this disease lead to morbidity and mortality. In this work, different localized calcifications of the aortic valve are studied for several grades of this disease and compared with the healthy case. For this purpose, single-phase FSI simulations of blood flow are performed for various degrees of localized calcification patterns and pertinent hemodynamic parameters are obtained. Critical flow parameters, transvalvular indexes and Wall Shear Stress (WSS) based indexes are discussed in detail.

Orijinal dilİngilizce
Ana bilgisayar yayını başlığıSIMULTECH 2023 - Proceedings of the 13th International Conference on Simulation and Modeling Methodologies, Technologies and Applications
EditörlerGerd Wagner, Frank Werner, Floriano De Rango
YayınlayanScience and Technology Publications, Lda
Sayfalar37-48
Sayfa sayısı12
ISBN (Basılı)9789897586682
DOI'lar
Yayın durumuYayınlandı - 2023
Etkinlik13th International Conference on Simulation and Modeling Methodologies, Technologies and Applications, SIMULTECH 2023 - Rome, Italy
Süre: 12 Tem 202314 Tem 2023

Yayın serisi

AdıProceedings of the International Conference on Simulation and Modeling Methodologies, Technologies and Applications
Hacim1
ISSN (Basılı)2184-2841

???event.eventtypes.event.conference???

???event.eventtypes.event.conference???13th International Conference on Simulation and Modeling Methodologies, Technologies and Applications, SIMULTECH 2023
Ülke/BölgeItaly
ŞehirRome
Periyot12/07/2314/07/23

Bibliyografik not

Publisher Copyright:
© 2023 by SCITEPRESS – Science and Technology Publications, Lda. All rights reserved.

Finansman

This work is funded by the Scientific and Technological Research Council of Turkey (TUBITAK) as ARDEB 1001 project under the grand number 120M671. Computing resources used in this work were provided by the National Center for High-Performance Computing of Turkey (UHeM) under grant number 5010662021.

FinansörlerFinansör numarası
National Center for High-Performance Computing of Turkey
Ulusal Yüksek Başarımlı Hesaplama Merkezi, Istanbul Teknik Üniversitesi5010662021
Türkiye Bilimsel ve Teknolojik Araştırma Kurumu120M671

    Parmak izi

    Hemodynamic characterization of localized aortic valve calcifications' araştırma başlıklarına git. Birlikte benzersiz bir parmak izi oluştururlar.

    Alıntı Yap