Effects of Cu2+ on stability and composition of water soluble ternary polyacrylic acid-Cu2+-protein complexes against radiation damage

M. I. Mastafaev; A. S. Saraç; A. Y. Erkol; S. Bayülken; B. Dinçer; E. Sezer

doi:10.1007/BF00342455

Effects of Cu²⁺ on stability and composition of water soluble ternary polyacrylic acid-Cu²⁺-protein complexes against radiation damage

M. I. Mastafaev^*, A. S. Saraç, A. Y. Erkol, S. Bayülken, B. Dinçer, E. Sezer

^*Bu çalışma için yazışmadan sorumlu yazar

Kimya Bölümü

Araştırma sonucu: Dergiye katkı › Makale › bilirkişi

6 Atıf (Scopus)

Özet

The formation of water soluble ternary complexes of polyacrylic acid (PAA) and bovine serum albumin (BSA) in the presence of divalent copper ions was investigated at the neutral pH. Aqueous solutions of PAA, BSA, and their mixture (PAA-BSA, PAA-Cu²⁺-BSA) have been irradiated with ⁶⁰Co γ-rays and the changes occurred have been measured by high performance liquid chromatography (HPLC) and spectrophotometry. Addition of Cu²⁺ ions to PAA-BSA mixture have been shown to protect the PAA and BSA components of ternary PAA-Cu²⁺-BSA complexes against radiation damage. A structural model of ternary polycomplexes was proposed and the mechanism of observed protection effect was discussed.

Orijinal dil	İngilizce
Sayfa (başlangıç-bitiş)	623-627
Sayfa sayısı	5
Dergi	Polymer Bulletin
Hacim	36
Basın numarası	5
DOI'lar	https://doi.org/10.1007/BF00342455
Yayın durumu	Yayınlandı - 1996

Belgeye Erişim

10.1007/BF00342455

Diğer Dosyalar ve Linkler

Link to publication in Scopus

Alıntı Yap

@article{ec93757959b54d178d2bfa26158b087f,

title = "Effects of Cu2+ on stability and composition of water soluble ternary polyacrylic acid-Cu2+-protein complexes against radiation damage",

abstract = "The formation of water soluble ternary complexes of polyacrylic acid (PAA) and bovine serum albumin (BSA) in the presence of divalent copper ions was investigated at the neutral pH. Aqueous solutions of PAA, BSA, and their mixture (PAA-BSA, PAA-Cu2+-BSA) have been irradiated with 60Co γ-rays and the changes occurred have been measured by high performance liquid chromatography (HPLC) and spectrophotometry. Addition of Cu2+ ions to PAA-BSA mixture have been shown to protect the PAA and BSA components of ternary PAA-Cu2+-BSA complexes against radiation damage. A structural model of ternary polycomplexes was proposed and the mechanism of observed protection effect was discussed.",

author = "Mastafaev, {M. I.} and Sara{\c c}, {A. S.} and Erkol, {A. Y.} and S. Bay{\"u}lken and B. Din{\c c}er and E. Sezer",

year = "1996",

doi = "10.1007/BF00342455",

language = "English",

volume = "36",

pages = "623--627",

journal = "Polymer Bulletin",

issn = "0170-0839",

publisher = "Springer Verlag",

number = "5",

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TY - JOUR

T1 - Effects of Cu2+ on stability and composition of water soluble ternary polyacrylic acid-Cu2+-protein complexes against radiation damage

AU - Mastafaev, M. I.

AU - Saraç, A. S.

AU - Erkol, A. Y.

AU - Bayülken, S.

AU - Dinçer, B.

AU - Sezer, E.

PY - 1996

Y1 - 1996

N2 - The formation of water soluble ternary complexes of polyacrylic acid (PAA) and bovine serum albumin (BSA) in the presence of divalent copper ions was investigated at the neutral pH. Aqueous solutions of PAA, BSA, and their mixture (PAA-BSA, PAA-Cu2+-BSA) have been irradiated with 60Co γ-rays and the changes occurred have been measured by high performance liquid chromatography (HPLC) and spectrophotometry. Addition of Cu2+ ions to PAA-BSA mixture have been shown to protect the PAA and BSA components of ternary PAA-Cu2+-BSA complexes against radiation damage. A structural model of ternary polycomplexes was proposed and the mechanism of observed protection effect was discussed.

AB - The formation of water soluble ternary complexes of polyacrylic acid (PAA) and bovine serum albumin (BSA) in the presence of divalent copper ions was investigated at the neutral pH. Aqueous solutions of PAA, BSA, and their mixture (PAA-BSA, PAA-Cu2+-BSA) have been irradiated with 60Co γ-rays and the changes occurred have been measured by high performance liquid chromatography (HPLC) and spectrophotometry. Addition of Cu2+ ions to PAA-BSA mixture have been shown to protect the PAA and BSA components of ternary PAA-Cu2+-BSA complexes against radiation damage. A structural model of ternary polycomplexes was proposed and the mechanism of observed protection effect was discussed.

UR - http://www.scopus.com/inward/record.url?scp=0001739863&partnerID=8YFLogxK

U2 - 10.1007/BF00342455

DO - 10.1007/BF00342455

M3 - Article

AN - SCOPUS:0001739863

SN - 0170-0839

VL - 36

SP - 623

EP - 627

JO - Polymer Bulletin

JF - Polymer Bulletin

IS - 5