Effective drug design screening in bacterial glycolytic enzymes via targeting alternative allosteric sites

Keyphrases

• Allosteric Site 100%
• Bacterial Strains 25%
• Binding Affinity 25%
• Candesartan Cilexetil 50%
• Catalytic Site 25%
• Design Screening 100%
• Dronedarone 25%
• Drug Candidates 25%
• Drug Compounds 25%
• Drug Design 100%
• Effective Compounds 100%
• Enzymatic Activity 25%
• Enzymatic Assay 50%
• FDA-approved Drugs 25%
• Glyceraldehyde-3-phosphate Dehydrogenase 25%
• Glycolytic Enzymes 100%
• Glycolytic Pathway 25%
• Growth Activity 25%
• Growth Inhibition 25%
• Human Host 25%
• In Vitro Experiment 25%
• Independent Screening 25%
• Inhibitory Effect 25%
• Killing Efficiency 25%
• Methicillin Resistance 50%
• Montelukast Sodium 25%
• Phosphofructokinase 25%
• Pyruvate Kinase 25%
• Screening Experiment 25%
• Staphylococcus Aureus 50%
• Targeting Strategies 25%
• Thonzonium Bromide 25%
• Top 10 25%

Pharmacology, Toxicology and Pharmaceutical Science

• 6 Phosphofructokinase 25%
• Antiinfective Agent 50%
• Candesartan Hexetil 50%
• Dronedarone 25%
• Glyceraldehyde 3 Phosphate Dehydrogenase 25%
• Glycolytic Enzyme 100%
• Meticillin 50%
• Montelukast 25%
• Pyruvate Kinase 25%
• Staphylococcus Aureus 50%
• Tonzonium Bromide 25%

Biochemistry, Genetics and Molecular Biology

• Allosteric Site 100%
• Bacterial Strain 20%
• Binding Affinity 20%
• Dronedarone 20%
• Enzyme 100%
• Enzyme Activity 20%
• Glyceraldehyde 3-Phosphate Dehydrogenase 20%
• Growth Inhibition 20%
• Montelukast 20%
• Phosphofructokinase 20%
• Pyruvate Kinase 20%
• Staphylococcus Aureus 40%