Covalent immobilization of lysozyme onto stainless steel as an anti-biofilm coating

Abdullah Sert, Emrah Yelboğa, Melek Tüter, Nevin Gül Karagüler*

*Bu çalışma için yazışmadan sorumlu yazar

Araştırma sonucu: ???type-name???Makalebilirkişi

1 Atıf (Scopus)

Özet

Covalent immobilization of an enzyme for use as antimicrobial biocompatible surface applications was performed utilizing the sol-gel chemistry, illustrated by chicken egg white lysozyme. The sol-gel network, which contains amine functional groups, provides covalent attachment sites for the enzyme via the carbodiimide reaction. As an alternative method, these free amine groups of the sol-gel layer were utilized for the immobilization of lysozyme from its N-terminus by using poly(acrylic acid) brushes as the linker molecule. The enzymatic activity of covalently immobilized lysozyme with both of the procedures has been investigated.

Orijinal dilİngilizce
Sayfa (başlangıç-bitiş)31-38
Sayfa sayısı8
DergiJournal of Cell and Molecular Biology
Hacim12
Basın numarası1-2
Yayın durumuYayınlandı - 1 Ara 2014

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Publisher Copyright:
© 2014 Journal of Cell and Molecular Biology. All rights reserved.

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