Biological particle manipulation: An example of Jurkat enrichment

Emre Altinagac; Huseyin Kizil; Levent Trabzon

doi:10.1049/mnl.2015.0185

Biological particle manipulation: An example of Jurkat enrichment

Emre Altinagac
, Huseyin Kizil
, Levent Trabzon

Istanbul Technical University

Araştırma çıktısı: Dergi yayını › Makale › Hakem

3 Atıf (Scopus)

Özet

Dielectrophoresis-based separation of microparticles and living cells are studied with computational and experimental methods. The flow behaviours of particles are modelled and simulated using COMSOL Multiphysics 4.3a software (COMSOL Ltd). Lab-on-a-chip devices having a titanium (Ti) interdigitated electrode layer on a glass substrate and a PDMS microchannel are fabricated to investigate the most effective design for separating particles based on their sizes. Polystyrene particles in different diameters (3.2 and 9.8 ìm) are used in the experiments. Green polystyrene particles from red ones are fully separated in a current design. Enrichment of Jurkat cells having 10.1 average diameter in phosphate buffer solution (PBS) medium is achieved.

Orijinal dil	İngilizce
Sayfa (başlangıç-bitiş)	550-553
Sayfa sayısı	4
Dergi	Micro and Nano Letters
Hacim	10
Basın numarası	10
DOI'lar	https://doi.org/10.1049/mnl.2015.0185
Yayın durumu	Yayınlandı - 1 Eki 2015

Bibliyografik not

Publisher Copyright:
© The Institution of Engineering and Technology 2015.

Belgeye Erişim

10.1049/mnl.2015.0185

Diğer Dosyalar ve Linkler

Link to publication in Scopus

Alıntı Yap

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title = "Biological particle manipulation: An example of Jurkat enrichment",

abstract = "Dielectrophoresis-based separation of microparticles and living cells are studied with computational and experimental methods. The flow behaviours of particles are modelled and simulated using COMSOL Multiphysics 4.3a software (COMSOL Ltd). Lab-on-a-chip devices having a titanium (Ti) interdigitated electrode layer on a glass substrate and a PDMS microchannel are fabricated to investigate the most effective design for separating particles based on their sizes. Polystyrene particles in different diameters (3.2 and 9.8 {\`i}m) are used in the experiments. Green polystyrene particles from red ones are fully separated in a current design. Enrichment of Jurkat cells having 10.1 average diameter in phosphate buffer solution (PBS) medium is achieved.",

author = "Emre Altinagac and Huseyin Kizil and Levent Trabzon",

note = "Publisher Copyright: {\textcopyright} The Institution of Engineering and Technology 2015.",

year = "2015",

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doi = "10.1049/mnl.2015.0185",

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TY - JOUR

T1 - Biological particle manipulation

T2 - An example of Jurkat enrichment

AU - Altinagac, Emre

AU - Kizil, Huseyin

AU - Trabzon, Levent

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Dielectrophoresis-based separation of microparticles and living cells are studied with computational and experimental methods. The flow behaviours of particles are modelled and simulated using COMSOL Multiphysics 4.3a software (COMSOL Ltd). Lab-on-a-chip devices having a titanium (Ti) interdigitated electrode layer on a glass substrate and a PDMS microchannel are fabricated to investigate the most effective design for separating particles based on their sizes. Polystyrene particles in different diameters (3.2 and 9.8 ìm) are used in the experiments. Green polystyrene particles from red ones are fully separated in a current design. Enrichment of Jurkat cells having 10.1 average diameter in phosphate buffer solution (PBS) medium is achieved.

AB - Dielectrophoresis-based separation of microparticles and living cells are studied with computational and experimental methods. The flow behaviours of particles are modelled and simulated using COMSOL Multiphysics 4.3a software (COMSOL Ltd). Lab-on-a-chip devices having a titanium (Ti) interdigitated electrode layer on a glass substrate and a PDMS microchannel are fabricated to investigate the most effective design for separating particles based on their sizes. Polystyrene particles in different diameters (3.2 and 9.8 ìm) are used in the experiments. Green polystyrene particles from red ones are fully separated in a current design. Enrichment of Jurkat cells having 10.1 average diameter in phosphate buffer solution (PBS) medium is achieved.

UR - https://www.scopus.com/pages/publications/84946238090

U2 - 10.1049/mnl.2015.0185

DO - 10.1049/mnl.2015.0185

M3 - Article

AN - SCOPUS:84946238090

SN - 1750-0443

VL - 10

SP - 550

EP - 553

JO - Micro and Nano Letters

JF - Micro and Nano Letters

IS - 10

ER -

Biological particle manipulation: An example of Jurkat enrichment

Özet

Bibliyografik not

Belgeye Erişim

Diğer Dosyalar ve Linkler

Parmak izi

Alıntı Yap