Aliphatic thioethers by s-alkylation of thiols via trialkyl borates

Deniz Gunes, Okan Sirkecioglu, Niyazi Bicak*

*Bu çalışma için yazışmadan sorumlu yazar

Araştırma sonucu: ???type-name???Makalebilirkişi

3 Atıf (Scopus)

Özet

A simple and convenient one-pot procedure is described for the synthesis of thioethers via boron esters. This procedure involves in-situ generation of alkyl sulfates by reaction of trialkyl borates with concentrated sulfuric acid and subsequent reaction with thiols in the presence of pyridine. The reactions with boron esters of primary or secondary alcohols proceed cleanly at 100C and afford aliphatic thioethers in reasonable yields (59-93%) within 24 h. Interestingly, the 1H NMR spectra of the products showed no sign of positional isomerisms. The method fails however with thiophenol and does not yield aromatic thioethers, due to electrophilic substitution at the phenyl ring.

Orijinal dilİngilizce
Sayfa (başlangıç-bitiş)1685-1690
Sayfa sayısı6
DergiPhosphorus, Sulfur and Silicon and the Related Elements
Hacim185
Basın numarası8
DOI'lar
Yayın durumuYayınlandı - Ağu 2010

Parmak izi

Aliphatic thioethers by s-alkylation of thiols via trialkyl borates' araştırma başlıklarına git. Birlikte benzersiz bir parmak izi oluştururlar.

Alıntı Yap