TY - JOUR
T1 - A short new route to the pyrido[2,3,4-kl]acridine subunit common to pyridoacridine alkaloids of marine origin
AU - Ali, Naji M.
AU - Chattopadhyay, Shital K.
AU - McKillop, Alexander
AU - Perret-Gentil, Roxanne M.
AU - Ozturk, Turan
AU - Rebelo, Ricardo A.
PY - 1992
Y1 - 1992
N2 - A short new route to the pyrido[2,3,4-kl]acridine ring system has been developed from readily available quinoline precursors involving two key steps: (i) a palladium(0)-catalysed Suzuki cross-coupling reaction of 4-chloroquinolines with arylboronic acids, and (ii) an intramolecular nitrene insertion reaction of the nitrenes derived from 4-phenyl-5-azidoquinolines.
AB - A short new route to the pyrido[2,3,4-kl]acridine ring system has been developed from readily available quinoline precursors involving two key steps: (i) a palladium(0)-catalysed Suzuki cross-coupling reaction of 4-chloroquinolines with arylboronic acids, and (ii) an intramolecular nitrene insertion reaction of the nitrenes derived from 4-phenyl-5-azidoquinolines.
UR - http://www.scopus.com/inward/record.url?scp=0026775181&partnerID=8YFLogxK
U2 - 10.1039/C39920001453
DO - 10.1039/C39920001453
M3 - Article
AN - SCOPUS:0026775181
SN - 0022-4936
SP - 1453
EP - 1454
JO - Chemical Communications
JF - Chemical Communications
IS - 19
ER -