Treatability of cefazolin antibiotic formulation effluent with O3 and O3/H2O2 processes

G. Iskender; A. Sezer; I. Arslan-Alaton; F. Germirli Babuna; O. S. Okay

doi:10.2166/wst.2007.325

Treatability of cefazolin antibiotic formulation effluent with O₃ and O₃/H₂O₂ processes

G. Iskender^*
, A. Sezer
, I. Arslan-Alaton
, F. Germirli Babuna
, O. S. Okay

^*Corresponding author for this work

Department of Environmental Engineering

Istanbul Technical University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

11 Citations (Scopus)

Abstract

The effect of applying ozonation and perozonation to antibiotic cefazolin-Na formulation effluents were investigated in this study. Twenty minutes of ozonation at a rate of 1,500 mg/L-h was observed to remove COD by 38%, whereas a COD removal efficiency of 40% was achieved via H₂O₂ enhanced ozonation (same conditions + 31.25 mM H₂O₂). Both of the pretreatment alternatives were monitored to elevate the BOD₅/COD ratio from 0.01 to 0.08. The initially inert COD was reduced by 38% using ozonation and by 60% employing H₂O₂ enhanced ozonation. In terms of the lowest achievable effluent COD levels after bio-treatment, ozonation was observed to yield a residual COD of 205 mg L^-1, while a residual COD of 135 mg L^-1 was involved for perozonation. According to the results of acute toxicity on Phaedactylum tricornutum, ozonated and perozonated samples exhibited more toxicity than the untreated effluent after 4 days. The activated sludge inhibition test demonstrated that both of the pretreatment alternatives efficiently eliminated the inhibition of investigated formulation effluent.

Original language	English
Title of host publication	Waste Management Problems in Agro-Industires 2006
Editors	D. Orhon, R. Tasli, O. Karahan, G.E. Zengin
Pages	217-225
Number of pages	9
Edition	10
DOIs	https://doi.org/10.2166/wst.2007.325
Publication status	Published - 2007

Publication series

Name	Water Science and Technology
Number	10
Volume	55
ISSN (Print)	0273-1223

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 6 Clean Water and Sanitation

Keywords

Activated sluidge inhibition
Acute toxicity
Advanced oxidation processes
Antibiotic formulation effluents
Chemical treatment
Inert COD
Pharmaceutical industry

Access to Document

10.2166/wst.2007.325

Cite this

Iskender, G., Sezer, A., Arslan-Alaton, I., Germirli Babuna, F., & Okay, O. S. (2007). Treatability of cefazolin antibiotic formulation effluent with O₃ and O₃/H₂O₂ processes. In D. Orhon, R. Tasli, O. Karahan, & G. E. Zengin (Eds.), Waste Management Problems in Agro-Industires 2006 (10 ed., pp. 217-225). (Water Science and Technology; Vol. 55, No. 10). https://doi.org/10.2166/wst.2007.325

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title = "Treatability of cefazolin antibiotic formulation effluent with O3 and O3/H2O2 processes",

abstract = "The effect of applying ozonation and perozonation to antibiotic cefazolin-Na formulation effluents were investigated in this study. Twenty minutes of ozonation at a rate of 1,500 mg/L-h was observed to remove COD by 38\%, whereas a COD removal efficiency of 40\% was achieved via H2O2 enhanced ozonation (same conditions + 31.25 mM H2O2). Both of the pretreatment alternatives were monitored to elevate the BOD5/COD ratio from 0.01 to 0.08. The initially inert COD was reduced by 38\% using ozonation and by 60\% employing H2O2 enhanced ozonation. In terms of the lowest achievable effluent COD levels after bio-treatment, ozonation was observed to yield a residual COD of 205 mg L-1, while a residual COD of 135 mg L-1 was involved for perozonation. According to the results of acute toxicity on Phaedactylum tricornutum, ozonated and perozonated samples exhibited more toxicity than the untreated effluent after 4 days. The activated sludge inhibition test demonstrated that both of the pretreatment alternatives efficiently eliminated the inhibition of investigated formulation effluent.",

keywords = "Activated sluidge inhibition, Acute toxicity, Advanced oxidation processes, Antibiotic formulation effluents, Chemical treatment, Inert COD, Pharmaceutical industry",

author = "G. Iskender and A. Sezer and I. Arslan-Alaton and \{Germirli Babuna\}, F. and Okay, \{O. S.\}",

year = "2007",

doi = "10.2166/wst.2007.325",

language = "English",

isbn = "1843395940",

series = "Water Science and Technology",

number = "10",

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Iskender, G, Sezer, A, Arslan-Alaton, I , Germirli Babuna, F & Okay, OS 2007, Treatability of cefazolin antibiotic formulation effluent with O₃ and O₃/H₂O₂ processes. in D Orhon, R Tasli, O Karahan & GE Zengin (eds), Waste Management Problems in Agro-Industires 2006. 10 edn, Water Science and Technology, no. 10, vol. 55, pp. 217-225. https://doi.org/10.2166/wst.2007.325

Treatability of cefazolin antibiotic formulation effluent with O₃ and O₃/H₂O₂ processes. / Iskender, G.; Sezer, A.; Arslan-Alaton, I. et al.
Waste Management Problems in Agro-Industires 2006. ed. / D. Orhon; R. Tasli; O. Karahan; G.E. Zengin. 10. ed. 2007. p. 217-225 (Water Science and Technology; Vol. 55, No. 10).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AB - The effect of applying ozonation and perozonation to antibiotic cefazolin-Na formulation effluents were investigated in this study. Twenty minutes of ozonation at a rate of 1,500 mg/L-h was observed to remove COD by 38%, whereas a COD removal efficiency of 40% was achieved via H2O2 enhanced ozonation (same conditions + 31.25 mM H2O2). Both of the pretreatment alternatives were monitored to elevate the BOD5/COD ratio from 0.01 to 0.08. The initially inert COD was reduced by 38% using ozonation and by 60% employing H2O2 enhanced ozonation. In terms of the lowest achievable effluent COD levels after bio-treatment, ozonation was observed to yield a residual COD of 205 mg L-1, while a residual COD of 135 mg L-1 was involved for perozonation. According to the results of acute toxicity on Phaedactylum tricornutum, ozonated and perozonated samples exhibited more toxicity than the untreated effluent after 4 days. The activated sludge inhibition test demonstrated that both of the pretreatment alternatives efficiently eliminated the inhibition of investigated formulation effluent.

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AN - SCOPUS:34249988779

SN - 1843395940

SN - 9781843395942

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BT - Waste Management Problems in Agro-Industires 2006

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