Transition metal complexes of propranolol dithiocarbamate: Synthesis, characterization, analytical properties and biological activity

Ayşegül Gölcü*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

52 Citations (Scopus)

Abstract

Propranolol dithiocarbamate (PDTC) and its complexes with Cu(II), Co(II), Ni(II), Zn(II) and Cd(II) have been synthesized and characterized by elemental analyses, FT-IR, electronic spectra, atomic absorption spectra, molar conductance, mass and 1H-n.m.r. spectral data. Information on the stoichiometry of the complexes was obtained from the continuous variation method (Job's method). The thermal decomposition behaviour of PDTC metal complexes was investigated in a nitrogen atmosphere using TG and DTA techniques. The antimicrobial activity studies of the metal complexes have been recorded against the Bacillus megaterium, Bacillus brevis, Yersinia enterocolitica, Micrococcus luteus, Pseudomonas aeruginosa, Enterococcus faecalis, Kluyveromyces marxianus, Candida tropicalis, Candida albicans and Kluvyeromyces fragilis.

Original languageEnglish
Pages (from-to)405-412
Number of pages8
JournalTransition Metal Chemistry
Volume31
Issue number3
DOIs
Publication statusPublished - Apr 2006
Externally publishedYes

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