Toxicity and biodegradability assessment of raw and ozonated procaine penicillin G formulation effluent

Idil Arslan-Alaton; Ali Efe Caglayan

doi:10.1016/j.ecoenv.2005.02.014

Toxicity and biodegradability assessment of raw and ozonated procaine penicillin G formulation effluent

Idil Arslan-Alaton^*
, Ali Efe Caglayan

^*Corresponding author for this work

Department of Environmental Engineering

Istanbul Technical University

Research output: Contribution to journal › Article › peer-review

97 Citations (Scopus)

Abstract

The effect of O₃ (applied dose=1440 mg h^-1; pH 7 and pH 12) and H₂O₂/O₃ (applied dose=1440 mg h ^-1; pH 7; 10 mM H₂O₂) pretreatment of procaine penicillin G (PPG) formulation effluent on its biodegradability and acute toxicity was investigated. For that purpose ISO 8192 activated sludge inhibition and Daphnia magna acute toxicity tests were conducted. BOD₅ measurements that were carried out to preevaluate the biocompatibility of untreated, ozonated, and perozonated PPG effluent have shown that BOD ₅ alone was not a very correct or useful tool to predict the actual biodegradability of PPG effluent. No significant correlation existed between the BOD₅ and the toxicity test results. Acute toxicity studies carried out with D. magna and synthetic municipal sewage sludge have demonstrated the inhibitory effect of H₂O₂/O₃ oxidation. COD removal of pharmaceutical wastewater containing PPG effluent with acclimated sewage sludge decreased from 79% to 50% after H₂O₂/O ₃ pretreatment.

Original language	English
Pages (from-to)	131-140
Number of pages	10
Journal	Ecotoxicology and Environmental Safety
Volume	63
Issue number	1
DOIs	https://doi.org/10.1016/j.ecoenv.2005.02.014
Publication status	Published - Jan 2006

Funding

The authors thank the Turkish National Scientific and Technology Research Council for their financial support under Project Ref. No. ICTAG–C-042.

Funders
Turkish National Scientific and Technology Research Council

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 6 Clean Water and Sanitation
SDG 7 Affordable and Clean Energy
SDG 9 Industry, Innovation, and Infrastructure
SDG 11 Sustainable Cities and Communities
SDG 12 Responsible Consumption and Production

Keywords

Activated sludge inhibition
Acute toxicity
Advanced oxidation processes (AOPs)
Antibiotic formulation effluent
Biodegradability
Ozonation
Pharmaceutical wastewater
Procaine penicillin G

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10.1016/j.ecoenv.2005.02.014

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title = "Toxicity and biodegradability assessment of raw and ozonated procaine penicillin G formulation effluent",

abstract = "The effect of O3 (applied dose=1440 mg h-1; pH 7 and pH 12) and H2O2/O3 (applied dose=1440 mg h -1; pH 7; 10 mM H2O2) pretreatment of procaine penicillin G (PPG) formulation effluent on its biodegradability and acute toxicity was investigated. For that purpose ISO 8192 activated sludge inhibition and Daphnia magna acute toxicity tests were conducted. BOD5 measurements that were carried out to preevaluate the biocompatibility of untreated, ozonated, and perozonated PPG effluent have shown that BOD 5 alone was not a very correct or useful tool to predict the actual biodegradability of PPG effluent. No significant correlation existed between the BOD5 and the toxicity test results. Acute toxicity studies carried out with D. magna and synthetic municipal sewage sludge have demonstrated the inhibitory effect of H2O2/O3 oxidation. COD removal of pharmaceutical wastewater containing PPG effluent with acclimated sewage sludge decreased from 79\% to 50\% after H2O2/O 3 pretreatment.",

keywords = "Activated sludge inhibition, Acute toxicity, Advanced oxidation processes (AOPs), Antibiotic formulation effluent, Biodegradability, Ozonation, Pharmaceutical wastewater, Procaine penicillin G",

author = "Idil Arslan-Alaton and Caglayan, \{Ali Efe\}",

year = "2006",

month = jan,

doi = "10.1016/j.ecoenv.2005.02.014",

language = "English",

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T1 - Toxicity and biodegradability assessment of raw and ozonated procaine penicillin G formulation effluent

AU - Arslan-Alaton, Idil

AU - Caglayan, Ali Efe

PY - 2006/1

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N2 - The effect of O3 (applied dose=1440 mg h-1; pH 7 and pH 12) and H2O2/O3 (applied dose=1440 mg h -1; pH 7; 10 mM H2O2) pretreatment of procaine penicillin G (PPG) formulation effluent on its biodegradability and acute toxicity was investigated. For that purpose ISO 8192 activated sludge inhibition and Daphnia magna acute toxicity tests were conducted. BOD5 measurements that were carried out to preevaluate the biocompatibility of untreated, ozonated, and perozonated PPG effluent have shown that BOD 5 alone was not a very correct or useful tool to predict the actual biodegradability of PPG effluent. No significant correlation existed between the BOD5 and the toxicity test results. Acute toxicity studies carried out with D. magna and synthetic municipal sewage sludge have demonstrated the inhibitory effect of H2O2/O3 oxidation. COD removal of pharmaceutical wastewater containing PPG effluent with acclimated sewage sludge decreased from 79% to 50% after H2O2/O 3 pretreatment.

AB - The effect of O3 (applied dose=1440 mg h-1; pH 7 and pH 12) and H2O2/O3 (applied dose=1440 mg h -1; pH 7; 10 mM H2O2) pretreatment of procaine penicillin G (PPG) formulation effluent on its biodegradability and acute toxicity was investigated. For that purpose ISO 8192 activated sludge inhibition and Daphnia magna acute toxicity tests were conducted. BOD5 measurements that were carried out to preevaluate the biocompatibility of untreated, ozonated, and perozonated PPG effluent have shown that BOD 5 alone was not a very correct or useful tool to predict the actual biodegradability of PPG effluent. No significant correlation existed between the BOD5 and the toxicity test results. Acute toxicity studies carried out with D. magna and synthetic municipal sewage sludge have demonstrated the inhibitory effect of H2O2/O3 oxidation. COD removal of pharmaceutical wastewater containing PPG effluent with acclimated sewage sludge decreased from 79% to 50% after H2O2/O 3 pretreatment.

KW - Activated sludge inhibition

KW - Acute toxicity

KW - Advanced oxidation processes (AOPs)

KW - Antibiotic formulation effluent

KW - Biodegradability

KW - Ozonation

KW - Pharmaceutical wastewater

KW - Procaine penicillin G

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M3 - Article

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AN - SCOPUS:29944433592

SN - 0147-6513

VL - 63

SP - 131

EP - 140

JO - Ecotoxicology and Environmental Safety

JF - Ecotoxicology and Environmental Safety

IS - 1

ER -

Toxicity and biodegradability assessment of raw and ozonated procaine penicillin G formulation effluent

Abstract

Funding

UN SDGs

Keywords

Access to Document

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