The use of novel photobleachable phthalocyanines to image DNA

Burcu Turanli-Yildiz, Tuba Sezgin, Z. Petek Akar, Canan Uslan, B. Şebnem Sesalan*, Ahmet Gül

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

The interaction of cationic photobleachable cobalt 1 and palladium 2 phthalocyanines (pcs) with calf thymus (CT) DNA was investigated by UV/vis spectrophotometric methods and gel electrophoresis. With the addition of pcs, the change in the thermal denaturation profile of DNA was observed. The results indicated that these molecules exhibit efficient DNA binding activity. The new cationic cobalt derivative 1 was characterized by elemental analysis, UV, IR and mass spectrophotometry.

Original languageEnglish
Pages (from-to)1720-1724
Number of pages5
JournalSynthetic Metals
Volume161
Issue number15-16
DOIs
Publication statusPublished - Aug 2011

Funding

This work was supported by the Research Funds of Istanbul Technical University (33851) and TUBITAK (110T527). We thank Dr. Barbaros Akkurt for UV/vis spectrophotometric measurements.

FundersFunder number
TUBITAK110T527
Istanbul Teknik Üniversitesi33851

    Keywords

    • DNA
    • Phthalocyanine
    • Water soluble

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