The synthesis of pyrido(2,3,4-,kl)acridine unit of some marine alkaloids

T. Ozturk; A. McKillop

doi:10.1139/v00-119

The synthesis of pyrido(2,3,4-,kl)acridine unit of some marine alkaloids

T. Ozturk^*
, A. McKillop

^*Corresponding author for this work

University of Waterloo

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

A simple and convenient synthesis of pyrido(2,3,4-kl)acridine (1), the main skeleton of some marine alkaloids, via cyclization and intramolecular nitrene insertion, is described. The importance of the planarity of the molecule during the nitrene insertion is explained.

Original language	English
Pages (from-to)	1158-1164
Number of pages	7
Journal	Canadian Journal of Chemistry
Volume	78
Issue number	9
DOIs	https://doi.org/10.1139/v00-119
Publication status	Published - 2000
Externally published	Yes

Keywords

Marine alkaloids
Nitrene insertion
Pyridoacridine
Quinoline
Quinolinone

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10.1139/v00-119

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title = "The synthesis of pyrido(2,3,4-,kl)acridine unit of some marine alkaloids",

abstract = "A simple and convenient synthesis of pyrido(2,3,4-kl)acridine (1), the main skeleton of some marine alkaloids, via cyclization and intramolecular nitrene insertion, is described. The importance of the planarity of the molecule during the nitrene insertion is explained.",

keywords = "Marine alkaloids, Nitrene insertion, Pyridoacridine, Quinoline, Quinolinone",

author = "T. Ozturk and A. McKillop",

year = "2000",

doi = "10.1139/v00-119",

language = "English",

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T1 - The synthesis of pyrido(2,3,4-,kl)acridine unit of some marine alkaloids

AU - Ozturk, T.

AU - McKillop, A.

PY - 2000

Y1 - 2000

N2 - A simple and convenient synthesis of pyrido(2,3,4-kl)acridine (1), the main skeleton of some marine alkaloids, via cyclization and intramolecular nitrene insertion, is described. The importance of the planarity of the molecule during the nitrene insertion is explained.

AB - A simple and convenient synthesis of pyrido(2,3,4-kl)acridine (1), the main skeleton of some marine alkaloids, via cyclization and intramolecular nitrene insertion, is described. The importance of the planarity of the molecule during the nitrene insertion is explained.

KW - Marine alkaloids

KW - Nitrene insertion

KW - Pyridoacridine

KW - Quinoline

KW - Quinolinone

UR - https://www.scopus.com/pages/publications/0033752885

U2 - 10.1139/v00-119

DO - 10.1139/v00-119

M3 - Article

AN - SCOPUS:0033752885

SN - 0008-4042

VL - 78

SP - 1158

EP - 1164

JO - Canadian Journal of Chemistry

JF - Canadian Journal of Chemistry

IS - 9

ER -

The synthesis of pyrido(2,3,4-,kl)acridine unit of some marine alkaloids

Abstract

Keywords

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