Abstract
A simple and convenient synthesis of pyrido(2,3,4-kl)acridine (1), the main skeleton of some marine alkaloids, via cyclization and intramolecular nitrene insertion, is described. The importance of the planarity of the molecule during the nitrene insertion is explained.
| Original language | English |
|---|---|
| Pages (from-to) | 1158-1164 |
| Number of pages | 7 |
| Journal | Canadian Journal of Chemistry |
| Volume | 78 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 2000 |
| Externally published | Yes |
Keywords
- Marine alkaloids
- Nitrene insertion
- Pyridoacridine
- Quinoline
- Quinolinone