The synergistic ramification of insoluble dietary fiber and associated non-extractable polyphenols on gut microbial population escorting alleviation of lifestyle diseases

Trina Das; Niloy Chatterjee; Esra Capanoglu; Jose M. Lorenzo; Arun K. Das; Pubali Dhar

doi:10.1016/j.fochx.2023.100697

The synergistic ramification of insoluble dietary fiber and associated non-extractable polyphenols on gut microbial population escorting alleviation of lifestyle diseases

Trina Das
, Niloy Chatterjee
, Esra Capanoglu
, Jose M. Lorenzo^*
, Arun K. Das
, Pubali Dhar

^*Corresponding author for this work

Department of Food Engineering

University of Calcutta
Parque Tecnológico de Galicia
University of Vigo
Indian Veterinary Research Institute

Research output: Contribution to journal › Review article › peer-review

36 Citations (Scopus)

Abstract

Most of the pertinent research which aims at exploring the therapeutic effects of polyphenols usually misapprehends a large fraction of non-extractable polyphenols due to their poor aqueous-organic solvent extractability. These polymeric polyphenols (i.e., proanthocyanins, hydrolysable tannins and phenolic acids) possess a unique property to adhere to the food matrix polysaccharides and protein sowing to their structural complexity with high glycosylation, degree of polymerization, and plenty of hydroxyl groups. Surprisingly resistance to intestinal absorption does not hinder its bioactivity but accelerates its functionality manifolds due to the colonic microbial catabolism in the gastrointestinal tract, thereby protecting the body from local and systemic inflammatory diseases. This review highlights not only the chemistry, digestion, colonic metabolism of non-extractable polyphenols (NEPP) but also summarises the synergistic effect of matrix-bound NEPP exerting local as well as systemic health benefits.

Original language	English
Article number	100697
Journal	Food Chemistry: X
Volume	18
DOIs	https://doi.org/10.1016/j.fochx.2023.100697
Publication status	Published - 30 Jun 2023

Bibliographical note

Publisher Copyright:
© 2023 The Author(s)

Funding

The authors would like to express their deepest gratitude to the University Grants Commission, Government of India, for supporting the research financially.Thanks to GAIN (Axencia Galega de Innovación) for supporting this review (grant number IN607A2019/01).

Funders	Funder number
University Grants Commission	IN607A2019/01

Keywords

Colonic fermentation
Food-matrix polysaccharide
Gut immune-modulation
Monomeric and polymeric polyphenols
Non-extractable polyphenols
Prebiotics

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10.1016/j.fochx.2023.100697

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title = "The synergistic ramification of insoluble dietary fiber and associated non-extractable polyphenols on gut microbial population escorting alleviation of lifestyle diseases",

abstract = "Most of the pertinent research which aims at exploring the therapeutic effects of polyphenols usually misapprehends a large fraction of non-extractable polyphenols due to their poor aqueous-organic solvent extractability. These polymeric polyphenols (i.e., proanthocyanins, hydrolysable tannins and phenolic acids) possess a unique property to adhere to the food matrix polysaccharides and protein sowing to their structural complexity with high glycosylation, degree of polymerization, and plenty of hydroxyl groups. Surprisingly resistance to intestinal absorption does not hinder its bioactivity but accelerates its functionality manifolds due to the colonic microbial catabolism in the gastrointestinal tract, thereby protecting the body from local and systemic inflammatory diseases. This review highlights not only the chemistry, digestion, colonic metabolism of non-extractable polyphenols (NEPP) but also summarises the synergistic effect of matrix-bound NEPP exerting local as well as systemic health benefits.",

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author = "Trina Das and Niloy Chatterjee and Esra Capanoglu and Lorenzo, \{Jose M.\} and Das, \{Arun K.\} and Pubali Dhar",

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doi = "10.1016/j.fochx.2023.100697",

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T1 - The synergistic ramification of insoluble dietary fiber and associated non-extractable polyphenols on gut microbial population escorting alleviation of lifestyle diseases

AU - Das, Trina

AU - Chatterjee, Niloy

AU - Capanoglu, Esra

AU - Lorenzo, Jose M.

AU - Das, Arun K.

AU - Dhar, Pubali

PY - 2023/6/30

Y1 - 2023/6/30

N2 - Most of the pertinent research which aims at exploring the therapeutic effects of polyphenols usually misapprehends a large fraction of non-extractable polyphenols due to their poor aqueous-organic solvent extractability. These polymeric polyphenols (i.e., proanthocyanins, hydrolysable tannins and phenolic acids) possess a unique property to adhere to the food matrix polysaccharides and protein sowing to their structural complexity with high glycosylation, degree of polymerization, and plenty of hydroxyl groups. Surprisingly resistance to intestinal absorption does not hinder its bioactivity but accelerates its functionality manifolds due to the colonic microbial catabolism in the gastrointestinal tract, thereby protecting the body from local and systemic inflammatory diseases. This review highlights not only the chemistry, digestion, colonic metabolism of non-extractable polyphenols (NEPP) but also summarises the synergistic effect of matrix-bound NEPP exerting local as well as systemic health benefits.

AB - Most of the pertinent research which aims at exploring the therapeutic effects of polyphenols usually misapprehends a large fraction of non-extractable polyphenols due to their poor aqueous-organic solvent extractability. These polymeric polyphenols (i.e., proanthocyanins, hydrolysable tannins and phenolic acids) possess a unique property to adhere to the food matrix polysaccharides and protein sowing to their structural complexity with high glycosylation, degree of polymerization, and plenty of hydroxyl groups. Surprisingly resistance to intestinal absorption does not hinder its bioactivity but accelerates its functionality manifolds due to the colonic microbial catabolism in the gastrointestinal tract, thereby protecting the body from local and systemic inflammatory diseases. This review highlights not only the chemistry, digestion, colonic metabolism of non-extractable polyphenols (NEPP) but also summarises the synergistic effect of matrix-bound NEPP exerting local as well as systemic health benefits.

KW - Colonic fermentation

KW - Food-matrix polysaccharide

KW - Gut immune-modulation

KW - Monomeric and polymeric polyphenols

KW - Non-extractable polyphenols

KW - Prebiotics

UR - https://www.scopus.com/pages/publications/85158134603

U2 - 10.1016/j.fochx.2023.100697

DO - 10.1016/j.fochx.2023.100697

M3 - Review article

AN - SCOPUS:85158134603

SN - 2590-1575

VL - 18

JO - Food Chemistry: X

JF - Food Chemistry: X

M1 - 100697

ER -

The synergistic ramification of insoluble dietary fiber and associated non-extractable polyphenols on gut microbial population escorting alleviation of lifestyle diseases

Abstract

Bibliographical note

Funding

Keywords

Access to Document

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