TY - JOUR
T1 - The state of the art in anti-aging
T2 - plant-based phytochemicals for skin care
AU - Tomas, Merve
AU - Günal-Köroğlu, Deniz
AU - Kamiloglu, Senem
AU - Ozdal, Tugba
AU - Capanoglu, Esra
N1 - Publisher Copyright:
© The Author(s) 2025.
PY - 2025/12
Y1 - 2025/12
N2 - Phytochemicals help mitigate skin aging by scavenging free radicals, modulating key enzymatic pathways, and promoting the skin’s structural integrity. Carotenoids, vitamins, essential fatty acids, and phenolic compounds work by acting as antioxidants, inhibiting enzymes like hyaluronidase, collagenase, and elastase, which degrade skin structure, and reducing levels of inflammatory markers (IL-6, IL-8, etc.) and matrix metalloproteinases (MMP-1, MMP-2) linked to aging. Recent research highlights that plant-based phytochemicals can improve skin elasticity, reduce hyperpigmentation, prevent the breakdown of important skin proteins, and support wound healing, making them valuable components for skin care and treatments. This review explores the multifaceted roles of phytochemicals in maintaining and improving skin health, highlighting their mechanisms of action and potential in skin anti-aging innovations.
AB - Phytochemicals help mitigate skin aging by scavenging free radicals, modulating key enzymatic pathways, and promoting the skin’s structural integrity. Carotenoids, vitamins, essential fatty acids, and phenolic compounds work by acting as antioxidants, inhibiting enzymes like hyaluronidase, collagenase, and elastase, which degrade skin structure, and reducing levels of inflammatory markers (IL-6, IL-8, etc.) and matrix metalloproteinases (MMP-1, MMP-2) linked to aging. Recent research highlights that plant-based phytochemicals can improve skin elasticity, reduce hyperpigmentation, prevent the breakdown of important skin proteins, and support wound healing, making them valuable components for skin care and treatments. This review explores the multifaceted roles of phytochemicals in maintaining and improving skin health, highlighting their mechanisms of action and potential in skin anti-aging innovations.
KW - Alkoloids
KW - Anti-aging
KW - Carotenoids
KW - Fatty acids
KW - Phytochemicals
KW - Polyphenols
KW - Saponins
KW - Skin care
UR - http://www.scopus.com/inward/record.url?scp=85217519437&partnerID=8YFLogxK
U2 - 10.1186/s12979-025-00498-9
DO - 10.1186/s12979-025-00498-9
M3 - Review article
AN - SCOPUS:85217519437
SN - 1742-4933
VL - 22
JO - Immunity and Ageing
JF - Immunity and Ageing
IS - 1
M1 - 5
ER -