The role of the corpus callosum in human cognition and anesthesia

Pelin Dilsiz, Sinem Sari*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Neurocognition is a substantially complex multi-component function. The corpus callosum (CC) is thought to conduct neurocognitive functions by providing communication and integration between both cerebral hemispheres. Regarding neurocognitive disorders, the changes in the CC support this argument. Exposure to anesthesia has been known to have short- and long-term effects on neurocognition. The pathophysiology of this dysfunction remains to be revealed. In this section, both the role of the CC in neurocognition and the relationship of the CC with neurocognitive disorders that develop after anesthesia exposure are discussed. Furthermore, anesthesia management is also discussed in the CC pathologies.

Original languageEnglish
Title of host publicationThe Corpus Callosum
Subtitle of host publicationEmbryology, Neuroanatomy, Neurophysiology, Neuropathology, and Surgery
PublisherSpringer International Publishing
Number of pages7
ISBN (Electronic)9783031381140
ISBN (Print)9783031381133
Publication statusPublished - 27 Nov 2023
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2023. All rights reserved.


  • Anesthesia management
  • Corpus callosum
  • Neurocognition
  • Postoperative cognitive dysfunction
  • White matter


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