Abstract
A water-soluble zinc phthalocyanine (Pc), ZnPc (3), bearing 12 dimethylamino groups, which enhance the solubility of the macrocycle was synthesized and characterized. Photobleaching of the compound was examined both invivo and invitro. Laser irradiation causes photo-oxidation of the newly synthesized ZnPc. A photobleachable phthalocyanine can be an alternative in imaging; phthalocyanine dyes are used in imaging the cardiovascular system. Besides, it can be used in fluorescein angiography in some cases. When compared to stable ones, a photobleaching ZnPc (3) might be an attractive compound for imaging in medicine.
| Original language | English |
|---|---|
| Pages (from-to) | 4319-4331 |
| Number of pages | 13 |
| Journal | Journal of Coordination Chemistry |
| Volume | 63 |
| Issue number | 24 |
| DOIs | |
| Publication status | Published - 20 Dec 2010 |
Funding
This study was supported by the Research Fund of Istanbul Technical University (31550). We thank R|dvan Sönmez and Dr Barbaros Akkurt for providing technical assistance.
| Funders | Funder number |
|---|---|
| Istanbul Teknik Üniversitesi | 31550 |
Keywords
- Cationic
- Dye
- Mice
- Photobleaching
- Phthalocyanine