Skip to main navigation Skip to search Skip to main content

The effect of external stimuli on the bovine serum albumin adsorption capacity of poly(acrylamide/maleic acid) hydrogels prepared by gamma rays

  • P. Akkaş
  • , M. Sari
  • , M. Şen*
  • , O. Güven
  • *Corresponding author for this work
  • Hacettepe University

Research output: Contribution to journalConference articlepeer-review

35 Citations (Scopus)

Abstract

The effects of external stimuli such as pH of the buffer solution, ionic strength, temperature and the amount of poly-electrolyte monomer in the hydrogel system on the Bovine Serum Albumin (BSA) adsorption capacity of poly(acrylamide/maleic acid) [P(AAm/MA)] hydrogels were investigated. Poly- electrolyte P(AAm/MA) hydrogels with varying compositions were prepared by irradiating acrylamide/maleic acid/water mixtures with γ rays at ambient temperature. Langmuir type adsorption isotherms were observed for all prepared hydrogels. Increase of ionic strength of the buffer solution from 0.01 to 0.1 mol dm-3 decreased the adsorption capacity of hydrogels and zero adsorption was observed in the presence of 0.1 mol dm-3 Na + and Ca2+ ion in the adsorption medium. The adsorption capacity of hydrogels was found to increase from 0 to 120 mg BSA/g dry gel, by changing external stimuli and hydrogel composition.

Original languageEnglish
Pages (from-to)717-721
Number of pages5
JournalRadiation Physics and Chemistry
Volume55
Issue number5-6
DOIs
Publication statusPublished - 1 Aug 1999
Externally publishedYes
EventProceedings of the 1998 9th Tihany Symposium on Radiation Chemistry - Tata, Hung
Duration: 29 Aug 19983 Sept 1998

Keywords

  • Adsorption
  • Bovine Serum Albumin
  • Hydrogel
  • Poly(acrylamide/maleic acid)

Fingerprint

Dive into the research topics of 'The effect of external stimuli on the bovine serum albumin adsorption capacity of poly(acrylamide/maleic acid) hydrogels prepared by gamma rays'. Together they form a unique fingerprint.

Cite this