The direct and indirect effects of bioactive compounds against coronavirus

Merve Tomas; Esra Capanoglu; Akbar Bahrami; Hamed Hosseini; Safoura Akbari-Alavijeh; Rezvan Shaddel; Abdur Rehman; Atefe Rezaei; Ali Rashidinejad; Farhad Garavand; Mostafa Goudarzi; Seid Mahdi Jafari

doi:10.1002/fft2.119

The direct and indirect effects of bioactive compounds against coronavirus

Merve Tomas, Esra Capanoglu^*, Akbar Bahrami, Hamed Hosseini, Safoura Akbari-Alavijeh, Rezvan Shaddel, Abdur Rehman, Atefe Rezaei, Ali Rashidinejad, Farhad Garavand, Mostafa Goudarzi, Seid Mahdi Jafari^*

^*Corresponding author for this work

Department of Food Engineering

Research output: Contribution to journal › Review article › peer-review

20 Citations (Scopus)

Abstract

Emerging viruses are known to pose a threat to humans in the world. COVID-19, a newly emerging viral respiratory disease, can spread quickly from people to people via respiratory droplets, cough, sneeze, or exhale. Up to now, there are no specific therapies found for the treatment of COVID-19. In this sense, the rising demand for effective antiviral drugs is stressed. The main goal of the present study is to cover the current literature about bioactive compounds (e.g., polyphenols, glucosinolates, carotenoids, minerals, vitamins, oligosaccharides, bioactive peptides, essential oils, and probiotics) with potential efficiency against COVID-19, showing antiviral activities via the inhibition of coronavirus entry into the host cell, coronavirus enzymes, as well as the virus replication in human cells. In turn, these compounds can boost the immune system, helping fight against COVID-19. Overall, it can be concluded that bioactives and the functional foods containing these compounds can be natural alternatives for boosting the immune system and defeating coronavirus.

Original language	English
Pages (from-to)	96-123
Number of pages	28
Journal	Food Frontiers
Volume	3
Issue number	1
DOIs	https://doi.org/10.1002/fft2.119
Publication status	Published - Mar 2022

Bibliographical note

Publisher Copyright:
© 2021 The Authors. Food Frontiers published by John Wiley & Sons Australia, Ltd and Nanchang University, Northwest University, Jiangsu University, Zhejiang University, Fujian Agriculture and Forestry University.

Keywords

COVID-19
antiviral activity
bioactive compounds
coronavirus
functional foods
immune system

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/fft2.119

Cite this

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abstract = "Emerging viruses are known to pose a threat to humans in the world. COVID-19, a newly emerging viral respiratory disease, can spread quickly from people to people via respiratory droplets, cough, sneeze, or exhale. Up to now, there are no specific therapies found for the treatment of COVID-19. In this sense, the rising demand for effective antiviral drugs is stressed. The main goal of the present study is to cover the current literature about bioactive compounds (e.g., polyphenols, glucosinolates, carotenoids, minerals, vitamins, oligosaccharides, bioactive peptides, essential oils, and probiotics) with potential efficiency against COVID-19, showing antiviral activities via the inhibition of coronavirus entry into the host cell, coronavirus enzymes, as well as the virus replication in human cells. In turn, these compounds can boost the immune system, helping fight against COVID-19. Overall, it can be concluded that bioactives and the functional foods containing these compounds can be natural alternatives for boosting the immune system and defeating coronavirus.",

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The direct and indirect effects of bioactive compounds against coronavirus

Abstract

Bibliographical note

Keywords

UN SDGs

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