Synthesis of highly functionalized γ-lactones via 1,5-electrocyclic ring closure

Olcay Anaç; F. Şeyma Güngör; Gökçe Merey

doi:10.1002/hlca.200690120

Synthesis of highly functionalized γ-lactones via 1,5-electrocyclic ring closure

Olcay Anaç^*, F. Şeyma Güngör, Gökçe Merey

^*Corresponding author for this work

Department of Chemistry

Istanbul Technical University

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

We have investigated 1,5-electrocyclic ring-closure reactions of conjugated esters with dimethyl diazomalonate in the presence of [Cu(acac)₂] as catalyst. Our new protocol offers an easy entry to various polyfunctionalized γ-lactones in high yields. Their subsequent derivatives may be used as valuable intermediates, especially in the synthesis of natural products and their analogues.

Original language	English
Pages (from-to)	1231-1240
Number of pages	10
Journal	Helvetica Chimica Acta
Volume	89
Issue number	6
DOIs	https://doi.org/10.1002/hlca.200690120
Publication status	Published - 2006

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title = "Synthesis of highly functionalized γ-lactones via 1,5-electrocyclic ring closure",

abstract = "We have investigated 1,5-electrocyclic ring-closure reactions of conjugated esters with dimethyl diazomalonate in the presence of [Cu(acac)2] as catalyst. Our new protocol offers an easy entry to various polyfunctionalized γ-lactones in high yields. Their subsequent derivatives may be used as valuable intermediates, especially in the synthesis of natural products and their analogues.",

author = "Olcay Ana{\c c} and G{\"u}ng{\"o}r, {F. {\c S}eyma} and G{\"o}k{\c c}e Merey",

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AU - Anaç, Olcay

AU - Güngör, F. Şeyma

AU - Merey, Gökçe

PY - 2006

Y1 - 2006

N2 - We have investigated 1,5-electrocyclic ring-closure reactions of conjugated esters with dimethyl diazomalonate in the presence of [Cu(acac)2] as catalyst. Our new protocol offers an easy entry to various polyfunctionalized γ-lactones in high yields. Their subsequent derivatives may be used as valuable intermediates, especially in the synthesis of natural products and their analogues.

AB - We have investigated 1,5-electrocyclic ring-closure reactions of conjugated esters with dimethyl diazomalonate in the presence of [Cu(acac)2] as catalyst. Our new protocol offers an easy entry to various polyfunctionalized γ-lactones in high yields. Their subsequent derivatives may be used as valuable intermediates, especially in the synthesis of natural products and their analogues.

UR - http://www.scopus.com/inward/record.url?scp=33745784168&partnerID=8YFLogxK

U2 - 10.1002/hlca.200690120

DO - 10.1002/hlca.200690120

M3 - Article

AN - SCOPUS:33745784168

SN - 0018-019X

VL - 89

SP - 1231

EP - 1240

JO - Helvetica Chimica Acta

JF - Helvetica Chimica Acta

IS - 6

ER -

Synthesis of highly functionalized γ-lactones via 1,5-electrocyclic ring closure

Abstract

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