Abstract
A new, convenient, one-pot process is presented for the synthesis of 2-oxazolines in high yields (75-94%) via boron esters of N-(2-hydroxyethyl) amides. The procedure involves thermolysis of the boron esters at 240-260 °C, in the presence of solid CaO as an acid scavenger and allows the preparation of oxazolines from hydroxyethyl amides of aliphatic and aromatic monocarboxylic acids.
Original language | English |
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Pages (from-to) | 5313-5315 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 51 |
Issue number | 40 |
DOIs | |
Publication status | Published - 6 Oct 2010 |