Synthesis, characterization, and in vitro bioactivity of sol-gel-derived Zn, Mg, and Zn-Mg co-doped bioactive glasses

Malek Erol*, Ayse Özyuguran, Özge Çelebican

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

Bioactive glasses in the systems CaO-SiO2-P2O5-ZnO, CaO-SiO2-P2O5-MgO, and CaO-SiO2-P2O5-MgO-ZnO were prepared and characterized. Bioactive glass powders were produced by the sol-gel method. The prepared bioactive glass powders were immersed in a simulated body fluid (SBF) for periods of up to 28 days at 310 K to investigate the bioactivity of the produced samples. Inductively coupled plasma (ICP) and ultraviolet (UV) spectroscopic techniques were used to detect changes in the SBF composition. X-Ray diffraction (XRD) was utilized to recognize and confirm the formation of a hydroxyapatite (HA) layer on the bioactive glass powders. Microstructural characterizations of the bioactive glass samples were investigated by scanning electron microscopy (SEM) techniques. Density, porosity, and surface area values of bioactive glass powders were also determined in order to characterize the textural properties of the samples. The results revealed the growth of an HA layer on the surface of the bioactive glass samples. MgO in the glass sample increases the rate of formation of an HA layer while ZnO in the glass slows it down.

Original languageEnglish
Pages (from-to)1066-1074
Number of pages9
JournalChemical Engineering and Technology
Volume33
Issue number7
DOIs
Publication statusPublished - Jul 2010

Keywords

  • Bioactive glass
  • Sol-gel method

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