Abstract
This study focuses on the biological properties of Ti6Al4V after employing micro-arc oxidation in sodium phosphateand calcium acetate-containing electrolyte with and without addition of silver acetate. After micro-arc oxidation process, structural features of the surfaces were analyzed by using an energy dispersive X-ray spectrometer equipped scanning electron microscope, an X-ray diffractometer and a Fourier transform infrared spectroscope. The micro-arc oxidation process generated multilayer coatings composed of carbonated hydroxyapatite and titanium oxide layers, while addition of 0001 mol/l silver acetate into the electrolyte caused incorporation of 07 wt.% silver into the coating. The antibacterial activity of the coatings was analyzed by using the Streptococcus mutans American Type Culture Collection 25175 strain. The metabolic activity of the multilayers was evaluated in cultures of a human primary osteogenic sarcoma cell line (Saos-2). In short, incorporation of 07 wt.% silver in the form of agglomerated particles, mostly around the micropores of the titanium oxide layer, enhanced the antibacterial efficiency of the fabricated coating to some extent without altering the cell proliferation considerably.
Original language | English |
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Pages (from-to) | 277-285 |
Number of pages | 9 |
Journal | Surface Innovations |
Volume | 6 |
Issue number | 4-5 |
DOIs | |
Publication status | Published - 13 Apr 2018 |
Funding
The authors grateful to the financial supports of the Scientific and Technological Research Council of Turkey (Tubitak) and Istanbul Technical University (ITU) through Tubitak Project Number 111M517 and Istanbul Technical University Scientific Research Projects Coordination Department Graduate Student Grant Number 38832. The authors also would like to express their thanks to Dr Grzegorz Cempura from the AGH University of Science and Technology for carrying out SEM investigations and Dr Selim Erturk for conducting AAS analyses.
Funders | Funder number |
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Istanbul Technical University Scientific Research Projects Coordination Department | 38832 |
Türkiye Bilimsel ve Teknolojik Araştirma Kurumu | |
Istanbul Teknik Üniversitesi | 111M517 |
Keywords
- Anti-bacterial
- Bioactive
- Surface modification