Abstract
Nanofibers offer potential applications in the biomedical field and they have become popular as they have the possibility to be produced for various fields ranging from drug encapsulation, drug delivery, tissue regeneration, wound and burn care, vascular grafts, enzyme immobilization, etc. due to their high surface area to volume ratio, ability to be suitable for biomimicry, possibility to be designed according to the application by optimization of nanofiber production process parameters, ability to enhance cell adhesion and growth and their ease of functionalization. Electrospinning is the most preferred method for the fabrication of nanofibers since it is a simple, versatile, and efficient technique. The nanofibers produced by electrospinning have the potential to be used in various applications including biomedical applications due to the ability of electrospinning to result in targeted fiber morphologies and diameters. In this chapter, the electrospinning process, parameters, and single and co-axial electrospinning techniques were explained. Moreover, biomedical applications especially wound dressing, tissue engineering, drug delivery, vascular grafts, and enzyme immobilization of nanofibers, with a focus on electrospun nanofibers were considered, and examples were reviewed in detail.
Original language | English |
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Title of host publication | Electrospun Nanofibers |
Subtitle of host publication | Principles, Technology and Novel Applications |
Publisher | Springer International Publishing |
Pages | 183-206 |
Number of pages | 24 |
ISBN (Electronic) | 9783030999582 |
ISBN (Print) | 9783030999575 |
DOIs | |
Publication status | Published - 1 Jan 2022 |
Bibliographical note
Publisher Copyright:© The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
Keywords
- Biomedical applications
- Biopolymers
- Electrospinning
- Nanofibers