Suitability of Electrospun Nanofibers for Specialized Biomedical Applications

Havva Ba Ş Kan, Hale Karakaş

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Nanofibers offer potential applications in the biomedical field and they have become popular as they have the possibility to be produced for various fields ranging from drug encapsulation, drug delivery, tissue regeneration, wound and burn care, vascular grafts, enzyme immobilization, etc. due to their high surface area to volume ratio, ability to be suitable for biomimicry, possibility to be designed according to the application by optimization of nanofiber production process parameters, ability to enhance cell adhesion and growth and their ease of functionalization. Electrospinning is the most preferred method for the fabrication of nanofibers since it is a simple, versatile, and efficient technique. The nanofibers produced by electrospinning have the potential to be used in various applications including biomedical applications due to the ability of electrospinning to result in targeted fiber morphologies and diameters. In this chapter, the electrospinning process, parameters, and single and co-axial electrospinning techniques were explained. Moreover, biomedical applications especially wound dressing, tissue engineering, drug delivery, vascular grafts, and enzyme immobilization of nanofibers, with a focus on electrospun nanofibers were considered, and examples were reviewed in detail.

Original languageEnglish
Title of host publicationElectrospun Nanofibers
Subtitle of host publicationPrinciples, Technology and Novel Applications
PublisherSpringer International Publishing
Pages183-206
Number of pages24
ISBN (Electronic)9783030999582
ISBN (Print)9783030999575
DOIs
Publication statusPublished - 1 Jan 2022

Bibliographical note

Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

Keywords

  • Biomedical applications
  • Biopolymers
  • Electrospinning
  • Nanofibers

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