Abstract
In this study, hydroxyapatite–chitosan composites with weight ratio of 1:0.1 were produced by spray-drying technique using two different inlet temperature. Besides, the effect of weight change of hydroxyapatite on composites was investigated on composites which were spray-dried in the selected temperature. Synthesized hydroxyapatite–chitosan samples were characterized using Fourier transform infrared microscopy, scanning electron microscopy, X-ray fluorescence spectroscopy, Brunauer–Emmet–Teller method, and X-ray diffraction. Particle size measurements were also performed in this content. Simulated body fluid studies were conducted on selected samples. According to results, hydroxyapatite–chitosan sample was successfully synthesized. Spray-dried mesoporous microspheres with high surface areas could be suitable for biomedical usage.
Original language | English |
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Pages (from-to) | 1172-1183 |
Number of pages | 12 |
Journal | Polymer - Plastics Technology and Engineering |
Volume | 54 |
Issue number | 11 |
DOIs | |
Publication status | Published - 5 Aug 2015 |
Bibliographical note
Publisher Copyright:© 2015, Copyright © Taylor & Francis Group, LLC.
Keywords
- Biomaterial
- Chitosan
- Hydroxyapatite
- Inlet temperature
- Spray-drying
- Weight change