Spray-Dried Mesoporous Hydroxyapatite–Chitosan Biocomposites

Tuğba Başargan*, Gülhayat Nasün-Saygılı

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


In this study, hydroxyapatite–chitosan composites with weight ratio of 1:0.1 were produced by spray-drying technique using two different inlet temperature. Besides, the effect of weight change of hydroxyapatite on composites was investigated on composites which were spray-dried in the selected temperature. Synthesized hydroxyapatite–chitosan samples were characterized using Fourier transform infrared microscopy, scanning electron microscopy, X-ray fluorescence spectroscopy, Brunauer–Emmet–Teller method, and X-ray diffraction. Particle size measurements were also performed in this content. Simulated body fluid studies were conducted on selected samples. According to results, hydroxyapatite–chitosan sample was successfully synthesized. Spray-dried mesoporous microspheres with high surface areas could be suitable for biomedical usage.

Original languageEnglish
Pages (from-to)1172-1183
Number of pages12
JournalPolymer - Plastics Technology and Engineering
Issue number11
Publication statusPublished - 5 Aug 2015

Bibliographical note

Publisher Copyright:
© 2015, Copyright © Taylor & Francis Group, LLC.


  • Biomaterial
  • Chitosan
  • Hydroxyapatite
  • Inlet temperature
  • Spray-drying
  • Weight change


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