Sperm motility analysis system implemented on a hybrid architecture to produce an intelligent analyzer

Osman Levent Şavkay*, Müştak E. Yalçın, Vedat Tavşanoğlu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Much research and analysis in biomedicine involve image and video inspection using microscopes. Presently, scientists are dissatisfied with manual observations and assessments, when objective and enhanced data can be obtained by applying new technologies (such as image and video inspection) to biomedical fields, such as sperm analysis. Computer Assisted Sperm Analysis (CASA) systems, developed in the late 1980s, constitute third-generation methods of sperm analysis. This study aimed to develop a standalone medical image and video analysis system that is reconfigurable, flexible, reliable, deterministic, and robust. It proposed a new sperm motility analysis system running on a dual core Central Processing Unit (CPU) + field programmable gate arrays (FPGA) platform, under a real-time operating system (RTOS), which is a step ahead of the third-generation CASA systems. The system hardware and related sperm detection and tracking algorithms were the novelty of this work. The image processing functions mainly run on FPGA, image acquisition, and calculations run on CPU, parallel with FPGA. The result is a much faster, reliable, reconfigurable, and compact intelligent analyzer system. Our prototype system was applied to sperm motility analysis; however, other image processing systems can be applied to this architecture. Additionally, the proposed tracking method for sperm track determination is simple, effective, and does not exert a load on the system.

Original languageEnglish
Article number100324
JournalInformatics in Medicine Unlocked
Volume19
DOIs
Publication statusPublished - 2020

Bibliographical note

Publisher Copyright:
© 2020

Funding

We are thankful to Prof. Dr. Erol Tavmergen, Ege University Family Planning, Infertility Research and Treatment Center, and the laboratory people at the center for their support, help and for providing human semen samples and comments on motility analysis. We also thank Gelişim Tıp (Medical) Laboratory for showing and introducing us to their CASA system, for taking semen sample videos and providing comments on sperm analysis. We are thankful to Assist. Prof. Dr. Kamber Demir, Dr. Ramazan Arıcı, Dr. Ahmet Eser from İstanbul University – Cerrahpaşa Faculty of Veterinary Medicine, Department of Reproduction and Artificial Insemination, for opening the laboratories, their comments and their help in conducting the tests and providing the samples.

FundersFunder number
Ege University Family Planning
Infertility Research and Treatment Center
İstanbul University – Cerrahpaşa Faculty of Veterinary Medicine, Department of Reproduction and Artificial Insemination

    Keywords

    • FPGA
    • Motility
    • Object determination
    • Real-time operating system
    • Sperm analysis
    • Tracking

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