Single cell array impedance analysis for cell detection and classification in a microfluidic device

Emre Altinagac; Selen Taskin; Huseyin Kizil

doi:10.5220/0006166700490053

Single cell array impedance analysis for cell detection and classification in a microfluidic device

Emre Altinagac, Selen Taskin, Huseyin Kizil

Department of Metallurgical and Materials Engineering

Istanbul Technical University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Citations (Scopus)

Abstract

Impedance analysis of single cells is presented in this paper. Following the separation of a target cell type by dielectrophoresis in our previous work, this paper focuses on capturing the cells as a single array and performing impedance analysis to point out the signature difference between each cell type. Lab-on-a-chip devices having a titanium interdigitated electrode layer on a glass substrate and a PDMS microchannel are fabricated to capture each cell in a single form and perform impedance analysis. MDA-MB-231 and HeLa cells are used in our experiments.

Original language	English
Title of host publication	BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017
Editors	Nathalia Peixoto, Ana Fred, Hugo Gamboa, Mario Vaz
Publisher	SciTePress
Pages	49-53
Number of pages	5
ISBN (Electronic)	9789897582165
DOIs	https://doi.org/10.5220/0006166700490053
Publication status	Published - 2017
Event	10th International Conference on Biomedical Electronics and Devices, BIODEVICES 2017 - Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017 - Porto, Portugal Duration: 21 Feb 2017 → 23 Feb 2017

Publication series

Name	BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017
Volume	2017-January

Conference

Conference	10th International Conference on Biomedical Electronics and Devices, BIODEVICES 2017 - Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017
Country/Territory	Portugal
City	Porto
Period	21/02/17 → 23/02/17

Bibliographical note

Publisher Copyright:
Copyright © 2017 by SCITEPRESS – Science and Technology Publications, Lda. All rights reserved.

Funding

The authors would like to acknowledge the financial support provided by the Scientific and Technological Research Council of Turkey (TUBITAK) under Grant No. 114M802.

Funders	Funder number
TUBITAK
Türkiye Bilimsel ve Teknolojik Araştirma Kurumu	114M802

Keywords

Impedance Analysis
Lab-on-a-Chip
Microfluidics
Single Cell Detection

Access to Document

10.5220/0006166700490053

Cite this

Altinagac, E., Taskin, S., & Kizil, H. (2017). Single cell array impedance analysis for cell detection and classification in a microfluidic device. In N. Peixoto, A. Fred, H. Gamboa, & M. Vaz (Eds.), BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017 (pp. 49-53). (BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017; Vol. 2017-January). SciTePress. https://doi.org/10.5220/0006166700490053

Altinagac, Emre ; Taskin, Selen ; Kizil, Huseyin. / Single cell array impedance analysis for cell detection and classification in a microfluidic device. BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017. editor / Nathalia Peixoto ; Ana Fred ; Hugo Gamboa ; Mario Vaz. SciTePress, 2017. pp. 49-53 (BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017).

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title = "Single cell array impedance analysis for cell detection and classification in a microfluidic device",

abstract = "Impedance analysis of single cells is presented in this paper. Following the separation of a target cell type by dielectrophoresis in our previous work, this paper focuses on capturing the cells as a single array and performing impedance analysis to point out the signature difference between each cell type. Lab-on-a-chip devices having a titanium interdigitated electrode layer on a glass substrate and a PDMS microchannel are fabricated to capture each cell in a single form and perform impedance analysis. MDA-MB-231 and HeLa cells are used in our experiments.",

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Altinagac, E, Taskin, S & Kizil, H 2017, Single cell array impedance analysis for cell detection and classification in a microfluidic device. in N Peixoto, A Fred, H Gamboa & M Vaz (eds), BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017. BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017, vol. 2017-January, SciTePress, pp. 49-53, 10th International Conference on Biomedical Electronics and Devices, BIODEVICES 2017 - Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017, Porto, Portugal, 21/02/17. https://doi.org/10.5220/0006166700490053

Single cell array impedance analysis for cell detection and classification in a microfluidic device. / Altinagac, Emre; Taskin, Selen; Kizil, Huseyin.
BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017. ed. / Nathalia Peixoto; Ana Fred; Hugo Gamboa; Mario Vaz. SciTePress, 2017. p. 49-53 (BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017; Vol. 2017-January).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Altinagac E, Taskin S, Kizil H. Single cell array impedance analysis for cell detection and classification in a microfluidic device. In Peixoto N, Fred A, Gamboa H, Vaz M, editors, BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017. SciTePress. 2017. p. 49-53. (BIODEVICES 2017 - 10th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017). doi: 10.5220/0006166700490053

Single cell array impedance analysis for cell detection and classification in a microfluidic device

Abstract

Publication series

Conference

Bibliographical note

Funding

Keywords

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