Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey

Gizem Alkurt; Ahmet Murt; Zeki Aydin; Ozge Tatli; Nihat Bugra Agaoglu; Arzu Irvem; Mehtap Aydin; Ridvan Karaali; Mustafa Gunes; Batuhan Yesilyurt; Hasan Turkez; Adil Mardinoglu; Mehmet Doganay; Filiz Basinoglu; Nurhan Seyahi; Gizem Dinler Doganay; Hamdi Levent Doganay

doi:10.1371/journal.pone.0247865

Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey

Gizem Alkurt
, Ahmet Murt
, Zeki Aydin
, Ozge Tatli
, Nihat Bugra Agaoglu
, Arzu Irvem
, Mehtap Aydin
, Ridvan Karaali
, Mustafa Gunes
, Batuhan Yesilyurt
, Hasan Turkez
, Adil Mardinoglu
, Mehmet Doganay
, Filiz Basinoglu
, Nurhan Seyahi
, Gizem Dinler Doganay
, Hamdi Levent Doganay

Department of Molecular Biology and Genetics

University of Health Sciences
Cerrahpasa Faculty of Medicine
Istanbul University - Cerrahpaşa
Department of Nephrology
Darica Farabi Teaching and Research Hospital
Department of Molecular Biology & Genetics
Istanbul Technical University
Department of Molecular Biology and Genetics
Istanbul Medeniyet University
Department of Microbiology
Department of Infectious Disease
Cerrahpaşa Faculty of Medicine
Department of Urology
Health Institutes of Turkey (TUSEB)
Faculty of Medicine
Ataturk University
KTH Royal Institute of Technology
King's College London
Faculty of Medicine
Lokman Hekim University
Department of Medical Biochemistry

Research output: Contribution to journal › Review article › peer-review

27 Citations (Scopus)

Abstract

COVID-19 is a global threat with an increasing number of infections. Research on IgG seroprevalence among health care workers (HCWs) is needed to re-evaluate health policies. This study was performed in three pandemic hospitals in Istanbul and Kocaeli. Different clusters of HCWs were screened for SARS-CoV-2 infection. Seropositivity rate among participants was evaluated by chemiluminescent microparticle immunoassay. We recruited 813 non-infected and 119 PCR-confirmed infected HCWs. Of the previously undiagnosed HCWs, 22 (2.7%) were seropositive. Seropositivity rates were highest for cleaning staff (6%), physicians (4%), nurses (2.2%) and radiology technicians (1%). Nonpandemic clinic (6.4%) and ICU (4.3%) had the highest prevalence. HCWs in "high risk"group had similar seropositivity rate with "no risk"group (2.9 vs 3.5 p = 0.7). These findings might lead to the re-evaluation of infection control and transmission dynamics in hospitals.

Original language	English
Article number	e0247865
Journal	PLoS ONE
Volume	16
Issue number	3 March
DOIs	https://doi.org/10.1371/journal.pone.0247865
Publication status	Published - Mar 2021

Bibliographical note

Publisher Copyright:
© 2021 Alkurt et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1371/journal.pone.0247865

Cite this

Alkurt, G., Murt, A., Aydin, Z., Tatli, O., Agaoglu, N. B., Irvem, A., Aydin, M., Karaali, R., Gunes, M., Yesilyurt, B., Turkez, H., Mardinoglu, A., Doganay, M., Basinoglu, F., Seyahi, N., Doganay, G. D., & Doganay, H. L. (2021). Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey. PLoS ONE, 16(3 March), Article e0247865. https://doi.org/10.1371/journal.pone.0247865

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title = "Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey",

abstract = "COVID-19 is a global threat with an increasing number of infections. Research on IgG seroprevalence among health care workers (HCWs) is needed to re-evaluate health policies. This study was performed in three pandemic hospitals in Istanbul and Kocaeli. Different clusters of HCWs were screened for SARS-CoV-2 infection. Seropositivity rate among participants was evaluated by chemiluminescent microparticle immunoassay. We recruited 813 non-infected and 119 PCR-confirmed infected HCWs. Of the previously undiagnosed HCWs, 22 (2.7\%) were seropositive. Seropositivity rates were highest for cleaning staff (6\%), physicians (4\%), nurses (2.2\%) and radiology technicians (1\%). Nonpandemic clinic (6.4\%) and ICU (4.3\%) had the highest prevalence. HCWs in {"}high risk{"}group had similar seropositivity rate with {"}no risk{"}group (2.9 vs 3.5 p = 0.7). These findings might lead to the re-evaluation of infection control and transmission dynamics in hospitals.",

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month = mar,

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Alkurt, G, Murt, A, Aydin, Z, Tatli, O, Agaoglu, NB, Irvem, A, Aydin, M, Karaali, R, Gunes, M, Yesilyurt, B, Turkez, H, Mardinoglu, A, Doganay, M, Basinoglu, F, Seyahi, N, Doganay, GD & Doganay, HL 2021, 'Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey', PLoS ONE, vol. 16, no. 3 March, e0247865. https://doi.org/10.1371/journal.pone.0247865

TY - JOUR

T1 - Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey

AU - Alkurt, Gizem

AU - Murt, Ahmet

AU - Aydin, Zeki

AU - Tatli, Ozge

AU - Agaoglu, Nihat Bugra

AU - Irvem, Arzu

AU - Aydin, Mehtap

AU - Karaali, Ridvan

AU - Gunes, Mustafa

AU - Yesilyurt, Batuhan

AU - Turkez, Hasan

AU - Mardinoglu, Adil

AU - Doganay, Mehmet

AU - Basinoglu, Filiz

AU - Seyahi, Nurhan

AU - Doganay, Gizem Dinler

AU - Doganay, Hamdi Levent

N1 - Publisher Copyright: © 2021 Alkurt et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PY - 2021/3

Y1 - 2021/3

N2 - COVID-19 is a global threat with an increasing number of infections. Research on IgG seroprevalence among health care workers (HCWs) is needed to re-evaluate health policies. This study was performed in three pandemic hospitals in Istanbul and Kocaeli. Different clusters of HCWs were screened for SARS-CoV-2 infection. Seropositivity rate among participants was evaluated by chemiluminescent microparticle immunoassay. We recruited 813 non-infected and 119 PCR-confirmed infected HCWs. Of the previously undiagnosed HCWs, 22 (2.7%) were seropositive. Seropositivity rates were highest for cleaning staff (6%), physicians (4%), nurses (2.2%) and radiology technicians (1%). Nonpandemic clinic (6.4%) and ICU (4.3%) had the highest prevalence. HCWs in "high risk"group had similar seropositivity rate with "no risk"group (2.9 vs 3.5 p = 0.7). These findings might lead to the re-evaluation of infection control and transmission dynamics in hospitals.

AB - COVID-19 is a global threat with an increasing number of infections. Research on IgG seroprevalence among health care workers (HCWs) is needed to re-evaluate health policies. This study was performed in three pandemic hospitals in Istanbul and Kocaeli. Different clusters of HCWs were screened for SARS-CoV-2 infection. Seropositivity rate among participants was evaluated by chemiluminescent microparticle immunoassay. We recruited 813 non-infected and 119 PCR-confirmed infected HCWs. Of the previously undiagnosed HCWs, 22 (2.7%) were seropositive. Seropositivity rates were highest for cleaning staff (6%), physicians (4%), nurses (2.2%) and radiology technicians (1%). Nonpandemic clinic (6.4%) and ICU (4.3%) had the highest prevalence. HCWs in "high risk"group had similar seropositivity rate with "no risk"group (2.9 vs 3.5 p = 0.7). These findings might lead to the re-evaluation of infection control and transmission dynamics in hospitals.

UR - https://www.scopus.com/pages/publications/85102468393

U2 - 10.1371/journal.pone.0247865

DO - 10.1371/journal.pone.0247865

M3 - Review article

C2 - 33657142

AN - SCOPUS:85102468393

SN - 1932-6203

VL - 16

JO - PLoS ONE

JF - PLoS ONE

IS - 3 March

M1 - e0247865

ER -

Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey

Abstract

Bibliographical note

UN SDGs

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