Santalum Genus: Phytochemical constituents, biological activities and health promoting-effects

Javad Sharifi-Rad; Cristina Quispe; Aknur Turgumbayeva; Zehra Mertdinç; Sena Tütüncü; Elif Feyza Aydar; Beraat Özçelik; Stȩpień Warda Anna; Staniak Mariola; Anna Koziróg; Anna Otlewska; Hubert Antolak; Surjit Sen; Krishnendu Acharya; Natallia Lapava; Simin Emamzadeh-Yazdi; Miquel Martorell; Manoj Kumar; Elena Maria Varoni; Marcello Iriti; Daniela Calina

doi:10.1515/znc-2022-0076

Santalum Genus: Phytochemical constituents, biological activities and health promoting-effects

Javad Sharifi-Rad^*
, Cristina Quispe
, Aknur Turgumbayeva
, Zehra Mertdinç
, Sena Tütüncü
, Elif Feyza Aydar
, Beraat Özçelik
, Stȩpień Warda Anna
, Staniak Mariola
, Anna Koziróg
, Anna Otlewska
, Hubert Antolak
, Surjit Sen
, Krishnendu Acharya
, Natallia Lapava
, Simin Emamzadeh-Yazdi
, Miquel Martorell
, Manoj Kumar
, Elena Maria Varoni
, Marcello Iriti^*

Daniela Calina^*

^*Corresponding author for this work

Department of Food Engineering

Research output: Contribution to journal › Review article › peer-review

36 Citations (Scopus)

Abstract

Santalum genus belongs to the family of Santalaceae, widespread in India, Australia, Hawaii, Sri Lanka, and Indonesia, and valued as traditional medicine, rituals and modern bioactivities. Sandalwood is reported to possess a plethora of bioactive compounds such as essential oil and its components (α-santalol and β-santalol), phenolic compounds and fatty acids. These bioactives play important role in contributing towards biological activities and health-promoting effects in humans. Pre-clinical and clinical studies have shown the role of sandalwood extract as antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroleptic, antihyperglycemic, antihyperlipidemic, and anticancer activities. Safety studies on sandalwood essential oil (EO) and its extracts have proven them as a safe ingredient to be utilized in health promotion. Phytoconstituents, bioactivities and traditional uses established sandalwood as one of the innovative materials for application in the pharma, food, and biomedical industry.

Original language	English
Pages (from-to)	9-25
Number of pages	17
Journal	Zeitschrift fur Naturforschung - Section C Journal of Biosciences
Volume	78
Issue number	1-2
DOIs	https://doi.org/10.1515/znc-2022-0076
Publication status	Published - 1 Jan 2023

Bibliographical note

Publisher Copyright:
© 2022 the author(s), published by De Gruyter, Berlin/Boston.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 9 Industry, Innovation, and Infrastructure

Keywords

bioactivities
clinical studies
essential oil
phytochemistry
safety
sandalwood

Access to Document

10.1515/znc-2022-0076

Cite this

Sharifi-Rad, J., Quispe, C., Turgumbayeva, A., Mertdinç, Z., Tütüncü, S., Aydar, E. F., Özçelik, B., Anna, S. W., Mariola, S., Koziróg, A., Otlewska, A., Antolak, H., Sen, S., Acharya, K., Lapava, N., Emamzadeh-Yazdi, S., Martorell, M., Kumar, M., Varoni, E. M., ... Calina, D. (2023). Santalum Genus: Phytochemical constituents, biological activities and health promoting-effects. Zeitschrift fur Naturforschung - Section C Journal of Biosciences, 78(1-2), 9-25. https://doi.org/10.1515/znc-2022-0076

@article{34062e35137c477db1e0cb7b5970c086,

title = "Santalum Genus: Phytochemical constituents, biological activities and health promoting-effects",

abstract = "Santalum genus belongs to the family of Santalaceae, widespread in India, Australia, Hawaii, Sri Lanka, and Indonesia, and valued as traditional medicine, rituals and modern bioactivities. Sandalwood is reported to possess a plethora of bioactive compounds such as essential oil and its components (α-santalol and β-santalol), phenolic compounds and fatty acids. These bioactives play important role in contributing towards biological activities and health-promoting effects in humans. Pre-clinical and clinical studies have shown the role of sandalwood extract as antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroleptic, antihyperglycemic, antihyperlipidemic, and anticancer activities. Safety studies on sandalwood essential oil (EO) and its extracts have proven them as a safe ingredient to be utilized in health promotion. Phytoconstituents, bioactivities and traditional uses established sandalwood as one of the innovative materials for application in the pharma, food, and biomedical industry.",

keywords = "bioactivities, clinical studies, essential oil, phytochemistry, safety, sandalwood",

author = "Javad Sharifi-Rad and Cristina Quispe and Aknur Turgumbayeva and Zehra Mertdin{\c c} and Sena T{\"u}t{\"u}nc{\"u} and Aydar, \{Elif Feyza\} and Beraat {\"O}z{\c c}elik and Anna, \{Stȩpie{\'n} Warda\} and Staniak Mariola and Anna Kozir{\'o}g and Anna Otlewska and Hubert Antolak and Surjit Sen and Krishnendu Acharya and Natallia Lapava and Simin Emamzadeh-Yazdi and Miquel Martorell and Manoj Kumar and Varoni, \{Elena Maria\} and Marcello Iriti and Daniela Calina",

note = "Publisher Copyright: {\textcopyright} 2022 the author(s), published by De Gruyter, Berlin/Boston.",

year = "2023",

month = jan,

day = "1",

doi = "10.1515/znc-2022-0076",

language = "English",

volume = "78",

pages = "9--25",

journal = "Zeitschrift fur Naturforschung - Section C Journal of Biosciences",

issn = "0939-5075",

publisher = "Walter de Gruyter GmbH",

number = "1-2",

}

Sharifi-Rad, J, Quispe, C, Turgumbayeva, A, Mertdinç, Z, Tütüncü, S, Aydar, EF , Özçelik, B, Anna, SW, Mariola, S, Koziróg, A, Otlewska, A, Antolak, H, Sen, S, Acharya, K, Lapava, N, Emamzadeh-Yazdi, S, Martorell, M, Kumar, M, Varoni, EM, Iriti, M & Calina, D 2023, 'Santalum Genus: Phytochemical constituents, biological activities and health promoting-effects', Zeitschrift fur Naturforschung - Section C Journal of Biosciences, vol. 78, no. 1-2, pp. 9-25. https://doi.org/10.1515/znc-2022-0076

TY - JOUR

T1 - Santalum Genus

T2 - Phytochemical constituents, biological activities and health promoting-effects

AU - Sharifi-Rad, Javad

AU - Quispe, Cristina

AU - Turgumbayeva, Aknur

AU - Mertdinç, Zehra

AU - Tütüncü, Sena

AU - Aydar, Elif Feyza

AU - Özçelik, Beraat

AU - Anna, Stȩpień Warda

AU - Mariola, Staniak

AU - Koziróg, Anna

AU - Otlewska, Anna

AU - Antolak, Hubert

AU - Sen, Surjit

AU - Acharya, Krishnendu

AU - Lapava, Natallia

AU - Emamzadeh-Yazdi, Simin

AU - Martorell, Miquel

AU - Kumar, Manoj

AU - Varoni, Elena Maria

AU - Iriti, Marcello

AU - Calina, Daniela

PY - 2023/1/1

Y1 - 2023/1/1

N2 - Santalum genus belongs to the family of Santalaceae, widespread in India, Australia, Hawaii, Sri Lanka, and Indonesia, and valued as traditional medicine, rituals and modern bioactivities. Sandalwood is reported to possess a plethora of bioactive compounds such as essential oil and its components (α-santalol and β-santalol), phenolic compounds and fatty acids. These bioactives play important role in contributing towards biological activities and health-promoting effects in humans. Pre-clinical and clinical studies have shown the role of sandalwood extract as antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroleptic, antihyperglycemic, antihyperlipidemic, and anticancer activities. Safety studies on sandalwood essential oil (EO) and its extracts have proven them as a safe ingredient to be utilized in health promotion. Phytoconstituents, bioactivities and traditional uses established sandalwood as one of the innovative materials for application in the pharma, food, and biomedical industry.

AB - Santalum genus belongs to the family of Santalaceae, widespread in India, Australia, Hawaii, Sri Lanka, and Indonesia, and valued as traditional medicine, rituals and modern bioactivities. Sandalwood is reported to possess a plethora of bioactive compounds such as essential oil and its components (α-santalol and β-santalol), phenolic compounds and fatty acids. These bioactives play important role in contributing towards biological activities and health-promoting effects in humans. Pre-clinical and clinical studies have shown the role of sandalwood extract as antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroleptic, antihyperglycemic, antihyperlipidemic, and anticancer activities. Safety studies on sandalwood essential oil (EO) and its extracts have proven them as a safe ingredient to be utilized in health promotion. Phytoconstituents, bioactivities and traditional uses established sandalwood as one of the innovative materials for application in the pharma, food, and biomedical industry.

KW - bioactivities

KW - clinical studies

KW - essential oil

KW - phytochemistry

KW - safety

KW - sandalwood

UR - https://www.scopus.com/pages/publications/85137656532

U2 - 10.1515/znc-2022-0076

DO - 10.1515/znc-2022-0076

M3 - Review article

C2 - 36069757

AN - SCOPUS:85137656532

SN - 0939-5075

VL - 78

SP - 9

EP - 25

JO - Zeitschrift fur Naturforschung - Section C Journal of Biosciences

JF - Zeitschrift fur Naturforschung - Section C Journal of Biosciences

IS - 1-2

ER -

Santalum Genus: Phytochemical constituents, biological activities and health promoting-effects

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this