Santalum Genus: Phytochemical constituents, biological activities and health promoting-effects

Javad Sharifi-Rad*, Cristina Quispe, Aknur Turgumbayeva, Zehra Mertdinç, Sena Tütüncü, Elif Feyza Aydar, Beraat Özçelik, Stȩpień Warda Anna, Staniak Mariola, Anna Koziróg, Anna Otlewska, Hubert Antolak, Surjit Sen, Krishnendu Acharya, Natallia Lapava, Simin Emamzadeh-Yazdi, Miquel Martorell, Manoj Kumar, Elena Maria Varoni, Marcello Iriti*Daniela Calina*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

20 Citations (Scopus)

Abstract

Santalum genus belongs to the family of Santalaceae, widespread in India, Australia, Hawaii, Sri Lanka, and Indonesia, and valued as traditional medicine, rituals and modern bioactivities. Sandalwood is reported to possess a plethora of bioactive compounds such as essential oil and its components (α-santalol and β-santalol), phenolic compounds and fatty acids. These bioactives play important role in contributing towards biological activities and health-promoting effects in humans. Pre-clinical and clinical studies have shown the role of sandalwood extract as antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroleptic, antihyperglycemic, antihyperlipidemic, and anticancer activities. Safety studies on sandalwood essential oil (EO) and its extracts have proven them as a safe ingredient to be utilized in health promotion. Phytoconstituents, bioactivities and traditional uses established sandalwood as one of the innovative materials for application in the pharma, food, and biomedical industry.

Original languageEnglish
Pages (from-to)9-25
Number of pages17
JournalZeitschrift fur Naturforschung - Section C Journal of Biosciences
Volume78
Issue number1-2
DOIs
Publication statusPublished - 1 Jan 2023

Bibliographical note

Publisher Copyright:
© 2022 the author(s), published by De Gruyter, Berlin/Boston.

Keywords

  • bioactivities
  • clinical studies
  • essential oil
  • phytochemistry
  • safety
  • sandalwood

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