Abstract
Microwave breast hyperthermia (MH) aims to increase the temperature at the tumor location with minimal change in the healthy tissue. To this end, the specific absorption rate ((Formula presented.)) inside the breast is optimized. The choice of the MH applicator design is important for a superior energy focus on the target. Although hyperthermia treatment planning (HTP) changes for every patient, the MH applicator is required to be effective for different breast models and tumor types. The linear applicator ((Formula presented.)) is one of the previously proposed applicator designs with linearly arranged antennas; however, it suffers from low focusing ability in certain breast regions due to its unsymmetrical geometrical features. In this paper, we propose to radially adjust the (Formula presented.) to obtain alternative excitation schemes without actually changing the applicator. Antipodal Vivaldi antennas were utilized, and the antenna excitations were optimized with particle swarm optimization (PSO). The comparison of the rotated and the fixed linear applicator, between 12-antenna circular and linear applicators, and finally, between a 24-antenna circular applicator are provided. Within the 12 rotation angles and two target locations that were analyzed, the 135° axially rotated linear applicator gave a 35% to 84% higher target-to-breast (Formula presented.) ratio ((Formula presented.)) and a 21% to 28% higher target-to-breast temperature ratio ((Formula presented.)) than the fixed linear applicator. For the deep-seated target, the 135° rotated linear applicator had an 80% higher (Formula presented.) and a 59% higher (Formula presented.) than the 12-antenna circular applicator, while the results were comparable to the 24-antenna circular applicator.
| Original language | English |
|---|---|
| Article number | 2677 |
| Journal | Diagnostics |
| Volume | 12 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Nov 2022 |
Bibliographical note
Publisher Copyright:© 2022 by the authors.
Funding
This work received funding from Scientific and Technological Research Council of Turkey under Grant Agreement 118S074 and COST Action Grant Agreement CA17115.
| Funders | Funder number |
|---|---|
| European Cooperation in Science and Technology | CA17115 |
| Türkiye Bilimsel ve Teknolojik Araştırma Kurumu | 118S074 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- antenna excitation optimization
- breast cancer
- hyperthermia treatment planning
- microwave hyperthermia
- particle swarm optimization
- specific absorption rate focus
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