Rosmarinic and carnosic acid contents and correlated antioxidant and antidiabetic activities of 14 Salvia species from Anatolia

Veselina Adımcılar, Zeynep Kalaycıoğlu, Nihal Aydoğdu, Tuncay Dirmenci, Ahmet Kahraman, F. Bedia Erim*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

Herbal medicine has been used worldwide as an alternative treatment. Salvia genus is one of the most remarked herbs which is traditionally used in the treatment of many diseases. Therefore, it is a crucial issue to reveal the chemical and biological profiles of different Salvia species. Rosmarinic and carnosic acid are the most well-known bioactive components generally accepted as the main antioxidant compounds in Salvia. This study firstly aims the determination of rosmarinic and carnosic acid contents of 14 Anatolian Salvia species by a simple and rapid capillary electrophoresis method. Moreover, the antioxidant activities and total phenolic contents of the Salvia samples were investigated. α-Glucosidase enzyme inhibitory effects of the samples were tested concerning their antidiabetic activities.

Original languageEnglish
Article number112763
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume175
DOIs
Publication statusPublished - 25 Oct 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier B.V.

Funding

We thank the Research Foundation of Istanbul Technical University for financial support.

FundersFunder number
Istanbul Teknik Üniversitesi

    Keywords

    • Antidiabetic activity
    • Antioxidant activity
    • Capillary electrophoresis
    • Rosmarinic acid
    • Salvia

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