Rosmarinic and carnosic acid contents and correlated antioxidant and antidiabetic activities of 14 Salvia species from Anatolia

Veselina Adımcılar; Zeynep Kalaycıoğlu; Nihal Aydoğdu; Tuncay Dirmenci; Ahmet Kahraman; F. Bedia Erim

doi:10.1016/j.jpba.2019.07.011

Rosmarinic and carnosic acid contents and correlated antioxidant and antidiabetic activities of 14 Salvia species from Anatolia

Veselina Adımcılar, Zeynep Kalaycıoğlu, Nihal Aydoğdu, Tuncay Dirmenci, Ahmet Kahraman, F. Bedia Erim^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

Herbal medicine has been used worldwide as an alternative treatment. Salvia genus is one of the most remarked herbs which is traditionally used in the treatment of many diseases. Therefore, it is a crucial issue to reveal the chemical and biological profiles of different Salvia species. Rosmarinic and carnosic acid are the most well-known bioactive components generally accepted as the main antioxidant compounds in Salvia. This study firstly aims the determination of rosmarinic and carnosic acid contents of 14 Anatolian Salvia species by a simple and rapid capillary electrophoresis method. Moreover, the antioxidant activities and total phenolic contents of the Salvia samples were investigated. α-Glucosidase enzyme inhibitory effects of the samples were tested concerning their antidiabetic activities.

Original language	English
Article number	112763
Journal	Journal of Pharmaceutical and Biomedical Analysis
Volume	175
DOIs	https://doi.org/10.1016/j.jpba.2019.07.011
Publication status	Published - 25 Oct 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier B.V.

Keywords

Antidiabetic activity
Antioxidant activity
Capillary electrophoresis
Rosmarinic acid
Salvia

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10.1016/j.jpba.2019.07.011

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title = "Rosmarinic and carnosic acid contents and correlated antioxidant and antidiabetic activities of 14 Salvia species from Anatolia",

abstract = "Herbal medicine has been used worldwide as an alternative treatment. Salvia genus is one of the most remarked herbs which is traditionally used in the treatment of many diseases. Therefore, it is a crucial issue to reveal the chemical and biological profiles of different Salvia species. Rosmarinic and carnosic acid are the most well-known bioactive components generally accepted as the main antioxidant compounds in Salvia. This study firstly aims the determination of rosmarinic and carnosic acid contents of 14 Anatolian Salvia species by a simple and rapid capillary electrophoresis method. Moreover, the antioxidant activities and total phenolic contents of the Salvia samples were investigated. α-Glucosidase enzyme inhibitory effects of the samples were tested concerning their antidiabetic activities.",

keywords = "Antidiabetic activity, Antioxidant activity, Capillary electrophoresis, Rosmarinic acid, Salvia",

author = "Veselina Adımcılar and Zeynep Kalaycıoğlu and Nihal Aydoğdu and Tuncay Dirmenci and Ahmet Kahraman and Erim, {F. Bedia}",

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doi = "10.1016/j.jpba.2019.07.011",

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T1 - Rosmarinic and carnosic acid contents and correlated antioxidant and antidiabetic activities of 14 Salvia species from Anatolia

AU - Adımcılar, Veselina

AU - Kalaycıoğlu, Zeynep

AU - Aydoğdu, Nihal

AU - Dirmenci, Tuncay

AU - Kahraman, Ahmet

AU - Erim, F. Bedia

PY - 2019/10/25

Y1 - 2019/10/25

N2 - Herbal medicine has been used worldwide as an alternative treatment. Salvia genus is one of the most remarked herbs which is traditionally used in the treatment of many diseases. Therefore, it is a crucial issue to reveal the chemical and biological profiles of different Salvia species. Rosmarinic and carnosic acid are the most well-known bioactive components generally accepted as the main antioxidant compounds in Salvia. This study firstly aims the determination of rosmarinic and carnosic acid contents of 14 Anatolian Salvia species by a simple and rapid capillary electrophoresis method. Moreover, the antioxidant activities and total phenolic contents of the Salvia samples were investigated. α-Glucosidase enzyme inhibitory effects of the samples were tested concerning their antidiabetic activities.

AB - Herbal medicine has been used worldwide as an alternative treatment. Salvia genus is one of the most remarked herbs which is traditionally used in the treatment of many diseases. Therefore, it is a crucial issue to reveal the chemical and biological profiles of different Salvia species. Rosmarinic and carnosic acid are the most well-known bioactive components generally accepted as the main antioxidant compounds in Salvia. This study firstly aims the determination of rosmarinic and carnosic acid contents of 14 Anatolian Salvia species by a simple and rapid capillary electrophoresis method. Moreover, the antioxidant activities and total phenolic contents of the Salvia samples were investigated. α-Glucosidase enzyme inhibitory effects of the samples were tested concerning their antidiabetic activities.

KW - Antidiabetic activity

KW - Antioxidant activity

KW - Capillary electrophoresis

KW - Rosmarinic acid

KW - Salvia

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ER -

Rosmarinic and carnosic acid contents and correlated antioxidant and antidiabetic activities of 14 Salvia species from Anatolia

Abstract

Bibliographical note

Keywords

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