Role of dietary antioxidants in neurodegenerative diseases: Where are we standing?

Sena Bakir, Gizem Catalkaya, Fatma D. Ceylan, Haroon Khan*, Burcu Guldiken, Esra Capanoglu, Mohammad A. Kamal

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

This review presents the potential effects of dietary antioxidants on neurodegenerative diseases. The relationship between autoimmunity and antioxidants, and their preventive effect on neurodegenerative diseases are evaluated. The driven factors of neurodegeneration and the potential effects of natural antioxidants are summarized for Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, spongiform encephalopathy, Huntington’s disease, and amyotrophic lateral sclerosis. The effect of oxidative stress on neurodegenerative diseases and regulative effect of antioxidants on oxidative balance is discussed. This review provides beneficial information for the possible cure of neurodegenerative diseases with dietary intake of antioxidants.

Original languageEnglish
Pages (from-to)714-729
Number of pages16
JournalCurrent Pharmaceutical Design
Volume26
Issue number7
DOIs
Publication statusPublished - 2020

Bibliographical note

Publisher Copyright:
© 2020 Bentham Science Publishers.

Keywords

  • Amyotrophic lateral sclerosis
  • Antioxidants
  • Dietary components
  • Encephalopathy
  • Immune system
  • Neurodegenerative diseases

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