Reward-predictive value in learning-related hippocampal neural activity

M. Okatan*, R. Komorowski, H. B. Eichenbaum

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We use point process likelihood models to explain the spiking activity of individual hippocampal pyramidal neurons as a function of task-relevant covariates and their Temporal Difference (TD) reward-predictive value during reinforcement learning. Our results suggest that CAl and CAJ neurons may signal information about the reward-predictive value of taskrelevant signals pertinent to the acquisition of behavioral strategies that maximize reward, with more CAl but not CAJ neurons doing so during novel versus familiar experiences.

Original languageEnglish
Title of host publicationNEBEC 2009 - Proceedings of the IEEE 35th Annual Northeast Bioengineering Conference
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781424443628
DOIs
Publication statusPublished - 2009
Externally publishedYes
EventIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009 - Boston, MA, United States
Duration: 3 Apr 20095 Apr 2009

Publication series

NameProceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
ISSN (Print)1071-121X

Conference

ConferenceIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009
Country/TerritoryUnited States
CityBoston, MA
Period3/04/095/04/09

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