TY - JOUR
T1 - Preparation of poly(oxanorbornene) based single and double-folding polymers via nucleophilic aromatic substitution reaction
AU - Alkan, Burcu
AU - Temel, Binnur Aydogan
AU - Durmaz, Hakan
AU - Temel, Gokhan
N1 - Publisher Copyright:
© 2023 Elsevier Ltd
PY - 2024/1/19
Y1 - 2024/1/19
N2 - A facile approach is introduced to prepare single-chain nanoparticles (SCNPs) utilizing intramolecular crosslinking based on nucleophilic aromatic substitution reaction. The linear polymeric precursor comprising dichlorotriazine (DCT) moiety as a reactive pendant group is synthesized via ring-opening metathesis polymerization (ROMP). The reactive chlorine atoms on DCT motifs are substituted with a dithiol nucleophile in varying degrees to yield individually intramolecularly crosslinked polymer nanoparticles. In addition, double-collapse and modification reactions are exploited through the substitution reaction from the remaining unreacted chlorine atoms. A significant reduction in hydrodynamic volumes of the corresponding SCNPs is observed compared to their linear analogues. The obtained nanoparticles are characterized by size exclusion chromatography (SEC), proton nuclear magnetic resonance spectroscopy (1H NMR), diffusion-ordered spectroscopy (DOSY), dynamic light scattering (DLS), and transmission electron microscopy (TEM) techniques.
AB - A facile approach is introduced to prepare single-chain nanoparticles (SCNPs) utilizing intramolecular crosslinking based on nucleophilic aromatic substitution reaction. The linear polymeric precursor comprising dichlorotriazine (DCT) moiety as a reactive pendant group is synthesized via ring-opening metathesis polymerization (ROMP). The reactive chlorine atoms on DCT motifs are substituted with a dithiol nucleophile in varying degrees to yield individually intramolecularly crosslinked polymer nanoparticles. In addition, double-collapse and modification reactions are exploited through the substitution reaction from the remaining unreacted chlorine atoms. A significant reduction in hydrodynamic volumes of the corresponding SCNPs is observed compared to their linear analogues. The obtained nanoparticles are characterized by size exclusion chromatography (SEC), proton nuclear magnetic resonance spectroscopy (1H NMR), diffusion-ordered spectroscopy (DOSY), dynamic light scattering (DLS), and transmission electron microscopy (TEM) techniques.
KW - Chain folding
KW - Cyanuric chloride
KW - Ring-opening metathesis polymerization
KW - Single–chain nanoparticles
KW - Soft nanoparticles
UR - http://www.scopus.com/inward/record.url?scp=85185846807&partnerID=8YFLogxK
U2 - 10.1016/j.eurpolymj.2023.112694
DO - 10.1016/j.eurpolymj.2023.112694
M3 - Article
AN - SCOPUS:85185846807
SN - 0014-3057
VL - 203
JO - European Polymer Journal
JF - European Polymer Journal
M1 - 112694
ER -