Abstract
The oxygenator is one of the most important components of respiratory support devices, which began as a heart-lung machine for the treatment of heart diseases. Hollow fiber membranes have been widely used in oxygenators due to their outstanding performance in oxygen and carbon dioxide exchange with the blood. In this review, general information on the oxygenator historical evolutions is summarized. Then, the advantages and usage of hollow fiber membranes as oxygenators are explained. Modification strategies to prevent platelet adhesion, plasma leakage have been summarized. There has been some information given on design parameters for hollow fiber membrane oxygenators. In recent years, the rapid development of microchannel structures in oxygenators has been summarized. It is thought that this review will help the reader to find recent studies on the subject.
Original language | English |
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Article number | 108340 |
Journal | Biochemical Engineering Journal |
Volume | 180 |
DOIs | |
Publication status | Published - Mar 2022 |
Bibliographical note
Publisher Copyright:© 2022 Elsevier B.V.
Funding
This study is supported by TUBITAK (The Scientific and Technological Research Council of Turkey) 118S108 ( 118S109 ) Grant Numbers.
Funders | Funder number |
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TUBITAK | |
Türkiye Bilimsel ve Teknolojik Araştirma Kurumu | 118S108, 118S109 |
Keywords
- Artificial lung
- Hollow fiber
- Membrane oxygenation
- Modification
- Oxygenator