Polyethyleneimine-coated capillaries for the separation of DNA by capillary electrophoresis

M. Said Nutku, F. Bedia Erim Berker*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

A new capillary electrophoresis of DNA fragments has been achieved with the cooperative effects of the electrophoretic and electroosmotic mobilities realized via the polyethyleneimine (PEI) coating of the capillary walls. As a result, seven of the 11 different-sized DNA fragments have produced resolved CE peaks. Our results demonstrate that analyses of DNA constituents can be performed under a wide range of conditions by the appropriate tuning of the coating and filler within the capillary.

Original languageEnglish
Pages (from-to)9-14
Number of pages6
JournalTurkish Journal of Chemistry
Volume27
Issue number1
Publication statusPublished - 2003

Keywords

  • Capillary electrophoresis
  • DNA
  • Polyethyleneimine

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