Plant-food-derived bioactives: Key health benefits and current nanosystems as a strategy to enhance their bioavailability

Bahare Salehi; Célia F. Rodrigues; Aslı Can Karaca; Gözde Gülseren; Ezgi Şenol; Evren Demircan; Beraat Özçelik; Sena Tutuncu; Farukh Sharopov; Javad Sharifi-Rad; Alfred Maroyi; Natália Martins

doi:10.14715/cmb/2020.66.4.28

Plant-food-derived bioactives: Key health benefits and current nanosystems as a strategy to enhance their bioavailability

Bahare Salehi
, Célia F. Rodrigues
, Aslı Can Karaca
, Gözde Gülseren
, Ezgi Şenol
, Evren Demircan
, Beraat Özçelik^*
, Sena Tutuncu
, Farukh Sharopov
, Javad Sharifi-Rad^*
, Alfred Maroyi^*
, Natália Martins^*

^*Corresponding author for this work

Department of Food Engineering

Bam University of Medical Sciences
University of Porto
Istanbul Technical University
BIOACTIVE Research & Innovation Food Manufac. Indust. Trade Ltd
Avicenna Tajik State Medical University
Shahid Beheshti University of Medical Sciences
University of Fort Hare

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

Natural products interest is gradually increasing worldwide. Plant-food-derived bioactives have a long history of use as a good source of ingredients for valuable medical usages. Plant-based foods consist of micro and macronutrients, and bioactive components, with health-promoting benefits. The handling of complex mixtures of plants has been methodically switched by therapies using a single isolated substance. The delivery of bioactive molecules in nanosystems is enhancing their bioavailability, it is much safer and cost-effective. However, there are many challenges in combining bioactive substances in nanocarrier materials. A discussion related with nanocarriers will be done in this review.

Original language	English
Pages (from-to)	232-242
Number of pages	11
Journal	Cellular and Molecular Biology
Volume	66
Issue number	4
DOIs	https://doi.org/10.14715/cmb/2020.66.4.28
Publication status	Published - 25 Jun 2020

Bibliographical note

Publisher Copyright:
Copyright: © 2020 by the C.M.B. Association. All rights reserved.

Funding

N. Martins would like to thank the Portuguese Foundation for Science and Technology (FCT-Portugal) for the Strategic project ref. UID/BIM/04293/2013 and “NORTE2020 - Programa Operacional Regional do Norte” (NORTE-01-0145-FEDER-000012) and C. F. Rodrigues for the UID/EQU/00511/2019 Project-Laboratory of Process Engineering, Environment, Biotechnology, and Energy-LEPABE financed by national funds through FCT/MCTES (PIDDAC).

Funders	Funder number
Fundação para a Ciência e a Tecnologia	UID/BIM/04293/2013, UID/EQU/00511/2019, NORTE-01-0145-FEDER-000012
Ministério da Ciência, Tecnologia e Ensino Superior

Keywords

Bioavailability
Drug delivery
Nanocarrier systems
Nutrients
Plant-food bioactives

Access to Document

10.14715/cmb/2020.66.4.28

Cite this

Salehi, B., Rodrigues, C. F., Karaca, A. C., Gülseren, G., Şenol, E., Demircan, E., Özçelik, B., Tutuncu, S., Sharopov, F., Sharifi-Rad, J., Maroyi, A., & Martins, N. (2020). Plant-food-derived bioactives: Key health benefits and current nanosystems as a strategy to enhance their bioavailability. Cellular and Molecular Biology, 66(4), 232-242. https://doi.org/10.14715/cmb/2020.66.4.28

@article{9ccea791b8e946a2bb6adb48d271ea98,

title = "Plant-food-derived bioactives: Key health benefits and current nanosystems as a strategy to enhance their bioavailability",

abstract = "Natural products interest is gradually increasing worldwide. Plant-food-derived bioactives have a long history of use as a good source of ingredients for valuable medical usages. Plant-based foods consist of micro and macronutrients, and bioactive components, with health-promoting benefits. The handling of complex mixtures of plants has been methodically switched by therapies using a single isolated substance. The delivery of bioactive molecules in nanosystems is enhancing their bioavailability, it is much safer and cost-effective. However, there are many challenges in combining bioactive substances in nanocarrier materials. A discussion related with nanocarriers will be done in this review.",

keywords = "Bioavailability, Drug delivery, Nanocarrier systems, Nutrients, Plant-food bioactives",

author = "Bahare Salehi and Rodrigues, \{C{\'e}lia F.\} and Karaca, \{Aslı Can\} and G{\"o}zde G{\"u}lseren and Ezgi {\c S}enol and Evren Demircan and Beraat {\"O}z{\c c}elik and Sena Tutuncu and Farukh Sharopov and Javad Sharifi-Rad and Alfred Maroyi and Nat{\'a}lia Martins",

year = "2020",

month = jun,

day = "25",

doi = "10.14715/cmb/2020.66.4.28",

language = "English",

volume = "66",

pages = "232--242",

journal = "Cellular and Molecular Biology",

issn = "0145-5680",

publisher = "Cellular and Molecular Biology Association",

number = "4",

}

Salehi, B, Rodrigues, CF, Karaca, AC, Gülseren, G, Şenol, E, Demircan, E , Özçelik, B, Tutuncu, S, Sharopov, F, Sharifi-Rad, J, Maroyi, A & Martins, N 2020, 'Plant-food-derived bioactives: Key health benefits and current nanosystems as a strategy to enhance their bioavailability', Cellular and Molecular Biology, vol. 66, no. 4, pp. 232-242. https://doi.org/10.14715/cmb/2020.66.4.28

TY - JOUR

T1 - Plant-food-derived bioactives

T2 - Key health benefits and current nanosystems as a strategy to enhance their bioavailability

AU - Salehi, Bahare

AU - Rodrigues, Célia F.

AU - Karaca, Aslı Can

AU - Gülseren, Gözde

AU - Şenol, Ezgi

AU - Demircan, Evren

AU - Özçelik, Beraat

AU - Tutuncu, Sena

AU - Sharopov, Farukh

AU - Sharifi-Rad, Javad

AU - Maroyi, Alfred

AU - Martins, Natália

PY - 2020/6/25

Y1 - 2020/6/25

N2 - Natural products interest is gradually increasing worldwide. Plant-food-derived bioactives have a long history of use as a good source of ingredients for valuable medical usages. Plant-based foods consist of micro and macronutrients, and bioactive components, with health-promoting benefits. The handling of complex mixtures of plants has been methodically switched by therapies using a single isolated substance. The delivery of bioactive molecules in nanosystems is enhancing their bioavailability, it is much safer and cost-effective. However, there are many challenges in combining bioactive substances in nanocarrier materials. A discussion related with nanocarriers will be done in this review.

AB - Natural products interest is gradually increasing worldwide. Plant-food-derived bioactives have a long history of use as a good source of ingredients for valuable medical usages. Plant-based foods consist of micro and macronutrients, and bioactive components, with health-promoting benefits. The handling of complex mixtures of plants has been methodically switched by therapies using a single isolated substance. The delivery of bioactive molecules in nanosystems is enhancing their bioavailability, it is much safer and cost-effective. However, there are many challenges in combining bioactive substances in nanocarrier materials. A discussion related with nanocarriers will be done in this review.

KW - Bioavailability

KW - Drug delivery

KW - Nanocarrier systems

KW - Nutrients

KW - Plant-food bioactives

UR - https://www.scopus.com/pages/publications/85087098168

U2 - 10.14715/cmb/2020.66.4.28

DO - 10.14715/cmb/2020.66.4.28

M3 - Review article

C2 - 32583797

AN - SCOPUS:85087098168

SN - 0145-5680

VL - 66

SP - 232

EP - 242

JO - Cellular and Molecular Biology

JF - Cellular and Molecular Biology

IS - 4

ER -

Plant-food-derived bioactives: Key health benefits and current nanosystems as a strategy to enhance their bioavailability

Abstract

Bibliographical note

Funding

Keywords

Access to Document

Other files and links

Fingerprint

Cite this