Phytochemicals of herbs and spices: Health versus toxicological effects

Burcu Guldiken, Gulay Ozkan, Gizem Catalkaya, Fatma Duygu Ceylan, Ipek Ekin Yalcinkaya, Esra Capanoglu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

105 Citations (Scopus)

Abstract

Phytochemicals are bioactive plant compounds that can be used as antimicrobial, antibacterial, anticancer agents and are reported to prevent cancer, cardiovascular and inflammatory diseases. Herbs and spices are rich in phytochemicals and can be consumed or used traditionally for medical or dietary purposes since the ancient times. However, there may be serious health risks for some population groups such as pregnant women and infants in the case of their unconscious and uncontrolled consumption. Several in vivo and in vitro studies related with the toxicological effects of phytochemicals in herbs and spices created awareness among consumers. These studies indicate the dose dependent effects of phytochemicals in herbs and spices showing toxicological effects at high doses whereas can also be health promoting at lower doses. In this review, two faces of herbs and spices were evaluated in every aspect.

Original languageEnglish
Pages (from-to)37-49
Number of pages13
JournalFood and Chemical Toxicology
Volume119
DOIs
Publication statusPublished - Sept 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Ltd

Keywords

  • Health effects
  • Herbs
  • Phytochemicals
  • Spices
  • Toxicological effects

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