Photophysical behaviour of cationic 2-(dimethylamino) ethanethio tetrasubstituted phthalocyanine complexes in the presence of gold nanoparticles

Thandekile P. Mthethwa; Yasin Arslanoglu; Edith Antunes; Tebello Nyokong

doi:10.1016/j.poly.2012.03.002

Photophysical behaviour of cationic 2-(dimethylamino) ethanethio tetrasubstituted phthalocyanine complexes in the presence of gold nanoparticles

Thandekile P. Mthethwa, Yasin Arslanoglu, Edith Antunes, Tebello Nyokong^*

^*Corresponding author for this work

Department of Basic Sciences

Rhodes University

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Magnesium and aluminium phthalocyanines tetrasubstituted with 2-(dimethylamino) ethanethiol have been synthesized (complexes 2 and 3). The prepared complexes were converted to water soluble ones by quaternizing with methyl iodide. The quaternized complexes (2Q, 3Q) show monomeric behaviour in organic solvents but show aggregation in water, especially for 2Q. Furthermore the water soluble complexes were conjugated with gold nanoparticles in DMSO to avoid aggregation of the phthalocyanines in water. The phthalocyanines showed a blue shift in their Q bands upon conjugation with gold nanoparticles. Low fluorescence quantum yields and lifetimes were also observed for the conjugates compared to the non-conjugated phthalocyanine molecules. The conjugated complexes showed an increase in the triplet quantum yields with a concomitant decrease in their triplet lifetimes.

Original language	English
Pages (from-to)	169-177
Number of pages	9
Journal	Polyhedron
Volume	38
Issue number	1
DOIs	https://doi.org/10.1016/j.poly.2012.03.002
Publication status	Published - 11 May 2012

Funding

This work was supported by the Department of Science and Technology (DST)/Nanotechnology (NIC) and National Research Foundation (NRF) of South Africa through DST/NRF South African Research Chairs Initiative for Professor of Medicinal Chemistry and Nanotechnology and Rhodes University.

Funders	Funder number
National Research Foundation
Rhodes University
Department of Science and Technology, Ministry of Science and Technology, India

Keywords

Aluminium
Gold nanoparticles
Magnesium
Photodynamic therapy
Phthalocyanine
Quaternized

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10.1016/j.poly.2012.03.002

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title = "Photophysical behaviour of cationic 2-(dimethylamino) ethanethio tetrasubstituted phthalocyanine complexes in the presence of gold nanoparticles",

abstract = "Magnesium and aluminium phthalocyanines tetrasubstituted with 2-(dimethylamino) ethanethiol have been synthesized (complexes 2 and 3). The prepared complexes were converted to water soluble ones by quaternizing with methyl iodide. The quaternized complexes (2Q, 3Q) show monomeric behaviour in organic solvents but show aggregation in water, especially for 2Q. Furthermore the water soluble complexes were conjugated with gold nanoparticles in DMSO to avoid aggregation of the phthalocyanines in water. The phthalocyanines showed a blue shift in their Q bands upon conjugation with gold nanoparticles. Low fluorescence quantum yields and lifetimes were also observed for the conjugates compared to the non-conjugated phthalocyanine molecules. The conjugated complexes showed an increase in the triplet quantum yields with a concomitant decrease in their triplet lifetimes.",

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AU - Mthethwa, Thandekile P.

AU - Arslanoglu, Yasin

AU - Antunes, Edith

AU - Nyokong, Tebello

PY - 2012/5/11

Y1 - 2012/5/11

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AB - Magnesium and aluminium phthalocyanines tetrasubstituted with 2-(dimethylamino) ethanethiol have been synthesized (complexes 2 and 3). The prepared complexes were converted to water soluble ones by quaternizing with methyl iodide. The quaternized complexes (2Q, 3Q) show monomeric behaviour in organic solvents but show aggregation in water, especially for 2Q. Furthermore the water soluble complexes were conjugated with gold nanoparticles in DMSO to avoid aggregation of the phthalocyanines in water. The phthalocyanines showed a blue shift in their Q bands upon conjugation with gold nanoparticles. Low fluorescence quantum yields and lifetimes were also observed for the conjugates compared to the non-conjugated phthalocyanine molecules. The conjugated complexes showed an increase in the triplet quantum yields with a concomitant decrease in their triplet lifetimes.

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KW - Gold nanoparticles

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KW - Phthalocyanine

KW - Quaternized

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Photophysical behaviour of cationic 2-(dimethylamino) ethanethio tetrasubstituted phthalocyanine complexes in the presence of gold nanoparticles

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Keywords

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