Phenolic compounds as natural microbial toxin detoxifying agents

Beyza Saricaoglu, Büşra Gültekin Subaşı, Funda Karbancioglu-Guler, Jose Manuel Lorenzo, Esra Capanoglu*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)


Despite the abundance of promising studies, developments, and improvements about the elimination of microbial toxins from food matrices, they are still considered as one of the major food safety problems due to the lack of their complete avoidance even today. Every year, many crops and foodstuffs have to be discarded due to unconstrained contamination and/or production of microbial toxins. Furthermore, the difficulty for the detection of toxin presence and determination of its level in foods may lead to acute or chronic health problems in many individuals. On the other hand, phenolic compounds might be considered as microbial toxin detoxification agents because of their inhibition effect on the toxin synthesis of microorganisms or exhibiting protective effects against varying damaging mechanisms caused by toxins. In this study, the effect of phenolic compounds on the synthesis of bacterial toxins and mycotoxins is comprehensively reviewed. The potential curing effect of phenolic compounds against toxin-induced damages has also been discussed. Consequently, phenolic compounds are indicated as promising, and considerable natural preservatives against toxin damages and their detoxification potentials are pronounced.

Original languageEnglish
Article number106989
Publication statusPublished - 15 Jan 2023

Bibliographical note

Publisher Copyright:
© 2022 Elsevier Ltd


J.M. Lorenzo thanks to GAIN (Axencia Galega de Innovación) for supporting this review (grant number IN607A201).

FundersFunder number
Axencia Galega de InnovaciónIN607A201


    • Aflatoxin
    • Bacterial toxins
    • Cholera toxin
    • Mycotoxins
    • Phenolic acid


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