Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder

Natália Cruz-Martins; Cristina Quispe; Celale Kirkin; Ezgi Şenol; Asli Zuluǧ; Beraat Özçelik; Adedayo O. Ademiluyi; Olubukola Helen Oyeniran; Prabhakar Semwal; Manoj Kumar; Farukh Sharopov; Victor López; Francisco Les; Iulia Cristina Bagiu; Monica Butnariu; Javad Sharifi-Rad; Mohammed M. Alshehri; William C. Cho

doi:10.1155/2021/1131280

Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder

Natália Cruz-Martins, Cristina Quispe, Celale Kirkin, Ezgi Şenol, Asli Zuluǧ, Beraat Özçelik, Adedayo O. Ademiluyi, Olubukola Helen Oyeniran, Prabhakar Semwal, Manoj Kumar, Farukh Sharopov, Victor López, Francisco Les^*, Iulia Cristina Bagiu, Monica Butnariu^*, Javad Sharifi-Rad^*, Mohammed M. Alshehri, William C. Cho^*

^*Corresponding author for this work

Department of Food Engineering

Research output: Contribution to journal › Review article › peer-review

7 Citations (Scopus)

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules.

Original language	English
Article number	1131280
Journal	Oxidative Medicine and Cellular Longevity
Volume	2021
DOIs	https://doi.org/10.1155/2021/1131280
Publication status	Published - 2021

Bibliographical note

Publisher Copyright:
© 2021 Natália Cruz-Martins et al.

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Cruz-Martins, N., Quispe, C., Kirkin, C., Şenol, E., Zuluǧ, A., Özçelik, B., Ademiluyi, A. O., Oyeniran, O. H., Semwal, P., Kumar, M., Sharopov, F., López, V., Les, F., Bagiu, I. C., Butnariu, M., Sharifi-Rad, J., Alshehri, M. M., & Cho, W. C. (2021). Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder. Oxidative Medicine and Cellular Longevity, 2021, Article 1131280. https://doi.org/10.1155/2021/1131280

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title = "Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder",

abstract = "Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules.",

author = "Nat{\'a}lia Cruz-Martins and Cristina Quispe and Celale Kirkin and Ezgi {\c S}enol and Asli Zuluǧ and Beraat {\"O}z{\c c}elik and Ademiluyi, {Adedayo O.} and Oyeniran, {Olubukola Helen} and Prabhakar Semwal and Manoj Kumar and Farukh Sharopov and Victor L{\'o}pez and Francisco Les and Bagiu, {Iulia Cristina} and Monica Butnariu and Javad Sharifi-Rad and Alshehri, {Mohammed M.} and Cho, {William C.}",

note = "Publisher Copyright: {\textcopyright} 2021 Nat{\'a}lia Cruz-Martins et al.",

year = "2021",

doi = "10.1155/2021/1131280",

language = "English",

volume = "2021",

journal = "Oxidative Medicine and Cellular Longevity",

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Cruz-Martins, N, Quispe, C, Kirkin, C, Şenol, E, Zuluǧ, A, Özçelik, B, Ademiluyi, AO, Oyeniran, OH, Semwal, P, Kumar, M, Sharopov, F, López, V, Les, F, Bagiu, IC, Butnariu, M, Sharifi-Rad, J, Alshehri, MM & Cho, WC 2021, 'Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder', Oxidative Medicine and Cellular Longevity, vol. 2021, 1131280. https://doi.org/10.1155/2021/1131280

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T1 - Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder

AU - Cruz-Martins, Natália

AU - Quispe, Cristina

AU - Kirkin, Celale

AU - Şenol, Ezgi

AU - Zuluǧ, Asli

AU - Özçelik, Beraat

AU - Ademiluyi, Adedayo O.

AU - Oyeniran, Olubukola Helen

AU - Semwal, Prabhakar

AU - Kumar, Manoj

AU - Sharopov, Farukh

AU - López, Victor

AU - Les, Francisco

AU - Bagiu, Iulia Cristina

AU - Butnariu, Monica

AU - Sharifi-Rad, Javad

AU - Alshehri, Mohammed M.

AU - Cho, William C.

PY - 2021

Y1 - 2021

N2 - Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules.

AB - Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules.

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DO - 10.1155/2021/1131280

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AN - SCOPUS:85114610989

SN - 1942-0900

VL - 2021

JO - Oxidative Medicine and Cellular Longevity

JF - Oxidative Medicine and Cellular Longevity

M1 - 1131280

ER -

Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder

Abstract

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