New atomic force microscopy based astrocyte cell shape index

Volkan Mujdat Tiryaki, Usienemfon Adia-Nimuwa, Steven Allen Hartz, Kan Xie, Virginia M. Ayres, Ijaz Ahmed, David I. Shreiber

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

A new three-dimensional cell shape index using the AFM height images of cells cultured on cell substrates was defined. The new cell shape index revealed quantitative cell spreading information of cells that is not included in the conventional cell shape index. The quantitative morphometry of rat cerebral cortical astrocytes cultured on four different kinds of cell substrates were investigated using the conventional and the new cell shape index, and the results were compared. The new cell shape index showed the quantitative astrocyte spreading and stellation behavior that agrees with the AFM height images of astrocytes.

Original languageEnglish
Title of host publicationScanning Probe Microscopy
Subtitle of host publicationFrontiers in Nanotechnology
PublisherMaterials Research Society
Pages14-19
Number of pages6
ISBN (Print)9781632661173
DOIs
Publication statusPublished - 2013
Externally publishedYes
Event2012 MRS Fall Meeting - Boston, MA, United States
Duration: 25 Nov 201230 Nov 2012

Publication series

NameMaterials Research Society Symposium Proceedings
Volume1527
ISSN (Print)0272-9172

Conference

Conference2012 MRS Fall Meeting
Country/TerritoryUnited States
CityBoston, MA
Period25/11/1230/11/12

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